Tumors of the Liver

Numerous advances in our understanding of the pathology and molecular features of liver tumors have been made since the publication of the previous series, nearly two decades ago. Examples of recent advances include the identification of novel entities, including their precursor lesions, the discovery of key molecular changes, including the fusion transcript between the DNAJB1 gene and the PRKACA gene in fibrolamellar carcinoma, the use of glutamine synthetase in the diagnosis of focal nodular hyperplasia, and the subtyping of hepatocellular adenomas using molecular and immunohistochemical methods. Together with the more unified classification and terminology of intrahepatic bile duct tumors and their precursors, these advances call for updated information that is presented in this volume.

Contents:

• 1. Embryology, Histology, and Anatomy
• 2. Benign Hepatocellular Tumors and Tumor-Like Lesions
• 3. Hepatocellular Carcinoma
• 4. Fibrolamellar Carcinoma
• 5. Pediatric Liver Tumors
• 6. Benign and Borderline Biliary Neoplasms and Tumor-Like Lesions
• 7. Intrahepatic Cholangiocarcinoma and Precursor Lesions
• 8. Combined Hepatocellular-Cholangiocarcinoma
• 9. Mesenchymal Tumors and Tumor-Like Lesions
• 10. Metastatic Disease
• 11. Lymphoid-Hematopoietic Tumors and Tumor-Like Lesions
• 12. Pathologic Staging of Primary Malignant Neoplasms in Liver