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Nadas’ Pediatric Cardiology, 3rd Edition
- Συγγραφείς: David W. Brown , Edward P. Walsh , John E. Mayer , Sarah A. Teele
- ISBN: 9781455705993
- Εκδότης: ELSEVIER
- Σελίδες: 848
- Έτος Έκδοσης: 2024
157,00€
168,00€
Χωρίς ΦΠΑ: 148,11€
In recent years, the field of pediatric cardiology has undergone rapid change, resulting in earlier diagnoses and improved long-term outcomes for many patients. Nadas’ Pediatric Cardiology, 3rd Edition, offers an easy-to-understand, practical, and team-based approach to this complex field, addressing the current needs of pediatric cardiologists, surgeons, fellows, and other members of the pediatric cardiology team. It thoroughly covers all diagnostic and management aspects of both acquired and congenital heart disease, providing a strong foundation and an actionable approach to care of the pediatric cardiology patient and family.
New to this edition
Features 7 new chapters including Sedation and Anesthesia; Cardiac Transplantation and Tissue Engineering; and Clinical Research.
Key Features
- Provides comprehensive coverage of the foundational and practical aspects of care for complex heart problems in children, covering both therapy and surgery from basic information through complex, team-based clinical applications.
- Includes new chapters on cardiomyopathies, structural heart disease, interventional procedures, genetics, electrophysiology, and imaging.
- Discusses the latest information on diagnosis and treatment of congenital heart disease, including in the fetus and young adult.
- Covers current drugs used in pediatric heart conditions and surgical therapy.
- Shares the knowledge and expertise of editors and authors at Boston Children’s Hospital, one of the world’s largest and most highly rated pediatric cardiology and congenital heart surgery institutions, using a team-based approach.
- Covers the full spectrum of care, including anesthesia, the ICU, and nursing considerations.
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.
TABLE OF CONTENTS
Cover image
Title page
Table of Contents
Copyright
Dedication
Contributors
Foreword
Preface
Video contents
List of Illustrations
List of Tables
Section I. Historical Notes
1. A brief history of pediatric cardiology and congenital heart surgery
References
Section II. Developmental Anatomy and Physiology
2. Cardiac embryology
Early human development
Week 3
Week 4
Week 5
Week 6
Week 7
Week 8
Acknowledgments
References
3. Morphologic-anatomic diagnosis: Normal and pathologic cardiac morphology
Cardiac structure
Heart location
Segmental morphology
Segmental analysis
Types of human hearts
Summary
Acknowledgments
References
4. Fetal and transitional circulation
Fetal circulation
Transitional circulation
References
Section III. Cardiac Genetics
5. Genetics of congenital heart disease
Introduction
Cardiac development
Clinical considerations
Conclusions
References
6. Dysmorphology and syndromes
Introduction
Patterns of syndromic congenital cardiac malformations
Teratogens
Chromosomal syndromes
Contiguous gene deletion syndromes
Single gene disorders
Reference
Section IV. Noninvasive Tools of Diagnosis
7. History, physical examination, oximetry, chest radiograph, and other baseline testing
Patient history
Physical examination
Routine laboratory tests
Acknowledgments
References
8. Electrocardiography
Cardiac electrical activity
The electrocardiogram
Ambulatory ECG monitoring
References
9. Echocardiography
Technical background
M-mode echocardiography
Two-dimensional echocardiography
Three-dimensional echocardiography
Doppler echocardiography
Contrast echocardiography
Objectives of the echocardiographic examination
Echocardiographic views
Interpretation and reporting
Quantitative analysis
Special echocardiographic procedures
Fetal echocardiography
Safety and complications
References
10. Advanced cardiac imaging
Magnetic resonance imaging
Cardiac computed tomography
References
11. Assessment of myocardial performance
Introduction
Myocardial versus ventricular mechanics
Systolic myocardial and ventricular mechanics
Diastolic myocardial and ventricular mechanics
Myocardial and ventricular compliance
Torsion
The effect of heart rate on cardiac performance
Understanding stress echocardiography basics: Assessment of ischemia
References
12. Exercise testing
Physiology of exercise
Central hemodynamics
Conduct of an exercise test
Interpretation of exercise physiology tests
References
Section V. Cardiac Catheterization
13. Fundamentals of cardiac catheterization
Introduction
Indications for cardiac catheterization
Risks of catheterization
Hemodynamic evaluation
Oxygen content and saturation
Angiographic evaluation
References
14. Interventional cardiac catheterization
Transcatheter valve dilation
Transcatheter valve replacement
Vascular interventions
Occlusion of shunts
Diagnostic and interventional catheterization in postoperative management
References
15. Lymphatic anomalies and interventions
Introduction
Basic lymphatic physiology and anatomy
Lymphatic abnormalities in congenital heart disease
Lymphatic imaging and interventions
References
16. Fetal cardiac interventions
Introduction
Aortic stenosis with evolving hypoplastic left heart syndrome
Fetal cardiac intervention for aortic stenosis: Procedure technique
Complications during fetal cardiac intervention procedure
Hypoplastic left heart syndrome with intact or highly restrictive atrial septum
Pulmonary atresia with intact ventricular septum
Technique: Fetal cardiac intervention for pulmonary atresia with intact ventricular septum
References
Section VI. Electrophysiology
17. Cardiac arrhythmias and antiarrhythmic drugs
Pathophysiology of arrhythmias
Premature beats
Tachycardias
Management of supraventricular tachycardia
Management of ventricular tachycardia
Sinus node dysfunction
Disorders of atrioventricular conduction
Pharmacologic therapy for arrhythmias
Conclusion
References
18. Electrophysiology studies and transcatheter ablation
Introduction
Historical experience and outcomes
Indications for electrophysiology study and ablation
Approach to anesthesia/sedation and periprocedural considerations
Equipment
Diagnostic electrophysiology study
Cardiac ablative technologies
Techniques for mapping and ablation of arrhythmias
Evaluation of ventricular arrhythmias
Complications of electrophysiology study and ablation
References
19. Pacemakers and anti-tachycardia devices
Pacemakers
Implantable cardioverter defibrillators
Complications
Device follow-up and remote monitoring
References
20. Inherited arrhythmia syndromes and arrhythmogenic cardiomyopathies
Introduction
Inherited arrhythmia syndromes
Arrhythmogenic cardiomyopathies
References
Section VII. Specific Congenital Heart Defects
21. Atrial septal defects
Definition
Prevalence
Embryology
Anatomy
Physiology
Clinical manifestations
Diagnostic techniques
Management
Course
Acknowledgment
References
22. Ventricular septal defects
Definition
Prevalence
Embryology
Etiology
Morphology/classification
Physiology
Associated anatomic disease
Clinical signs and symptoms
Diagnosis
Prognosis
Treatment
Intervention for VSD closure
References
23. Anomalies of the ductus arteriosus
Definition
Prevalence
Anatomy
Physiology
Clinical manifestations
Course
Management
Variations
Acknowledgment
References
24. Coarctation of the aorta and interrupted aortic arch
Coarctation
Interrupted aortic arch
References
25. Pulmonary stenosis
Definition
Prevalence
Anatomy
Physiology
Valvar pulmonary stenosis
Dysplastic pulmonary valve
Pulmonary regurgitation
Peripheral pulmonary stenosis
References
26. Tetralogy of fallot
Definition
Prevalence and genetics
Pathology
Physiology
Clinical manifestations
Electrocardiography
Chest radiography
Echocardiography
Cardiac catheterization
Other studies
Management and course
References
27. Double-outlet right ventricle
Definition
Prevalence
Pathology
References
28. Aortic outflow abnormalities
Introduction
Valvar aortic stenosis
Subaortic stenosis
Supravalvar aortic stenosis
Aortic regurgitation
References
29. D-transposition of the great arteries
Definition
Prevalence
Embryology
Anatomy
Physiology
Clinical manifestations
Cardiac computed tomography
Preoperative management
Course following atrial switch repair
Course following arterial switch procedure
Variations
Summary
References
30. Congenitally corrected transposition of the great arteries
Definition
Prevalence
Anatomy
Physiology
Clinical manifestations
Management
Course
Anatomically corrected malposition of the great arteries
References
31. Atrioventricular canal defects
Definition
Embryology and genetics
Anatomy and classification
Pathophysiology and clinical course
Diagnosis
Management
Complete atrioventricular canal defect
Transitional atrioventricular canal defect
Partial atrioventricular canal defect
Postoperative management
Short- and long-term outcomes
Care of adults with repaired atrioventricular canal defect
nces
32. Heterotaxy syndrome
Introduction
Definitions and nomenclature
Prevalence and etiology
Cardiac manifestations and diagnostic tools
Multidisciplinary approach to heterotaxy care
Acknowledgments
References
33. Mitral valve and left atrial abnormalities
Mitral valve disease
Left atrial problems
References
34. Ebstein anomaly and other tricuspid valve problems
Ebstein anomaly
Other tricuspid valve problems
References
35. Hypoplastic left heart syndrome
Definition
Prevalence and genetics
Anatomy
Physiology
Diagnosis and clinical manifestations
Management
Cardiac transplantation
Ethical issues
Other anatomic variants of HLHS
Aortic atresia with normal left ventricle
References
36. Tricuspid atresia
Definition
Prevalence
Anatomy
Physiology
Clinical manifestations
Management
Course
References
37. Pulmonary atresia with intact ventricular septum
Definition
Prevelance
Prenatal development
Morphology
Physiology
Clinical presentation
Diagnostic evaluation
Management
Prognosis
References
38. Truncus arteriosus and hemitruncus
Truncus arteriosus
Prevalence
Embryology
Anatomy
Physiology
Clinical manifestations
Management
Hemitruncus (origin of branch pulmonary artery from the ascending aorta)
Definition
Prevalence
Embryology
Pathology
Physiology
Clinical manifestations
Management
Acknowledgment
References
39. Total anomalous pulmonary venous connection
Definition
Incidence
Embryology
Anatomy
Physiology
Clinical manifestations
Management
Clinical course
References
40. Pulmonary vein stenosis
Clinical description
Risk factors and prognosis
Management
Surveillance and involvement of subspecialists
References
41. Aortopulmonary window
Definition
Prevalence
Embryology
Anatomy
Physiology
Clinical manifestations
Management
References
42. Coronary artery anomalies
Introduction
Anomalous origin of the left coronary artery from a pulmonary artery
Anomalous aortic origin of the coronary artery
Intraseptal or intraconal left coronary artery
Coronary arterial fistulae
References
43. Vascular rings, slings, and related anomalies
Normal left aortic arch
Aortic arch variants
Vascular rings
Pulmonary artery sling
Innominate artery compression syndrome
Isolated branch pulmonary artery
References
Section VIII. Other Forms of Heart Disease
44. Preventive cardiology
Introduction
Hypertension
Dyslipidemia
Nicotine, physical activity, and cardiovascular disease
Conclusion
References
45. Rheumatic fever and rheumatic heart disease
Introduction
Epidemiology
Pathogenesis
Pathology
Clinical manifestations
Ancillary studies
Diagnosis
Management
Prevention
Acknowledgment
References
46. Kawasaki disease
Definition
Prevalence
Etiology and pathogenesis
Pathology
Clinical manifestations
Management
Long-term follow-up
References
47. Lyme disease, COVID-19, and myocarditis
Lyme disease
Coronavirus disease 2019
Multisystem inflammatory syndrome in children
Myocarditis
References
48. Cardiomyopathies
Introduction
Dilated cardiomyopathy
Specific subtypes of DCM
Left ventricular non-compaction cardiomyopathy
Hypertrophic cardiomyopathy
Restrictive cardiomyopathy
References
49. Pericardial disease
Introduction
Pericarditis
Recurrent pericarditis
Post-pericardiotomy syndrome
Noninflammatory pericardial effusions
Tamponade
Constrictive pericardial disease
Congenital partial or complete absence of the pericardium
Pericardial cysts and masses
References
50. Infective endocarditis
Introduction
Epidemiology
Pathophysiology
Diagnosis
Treatment
Complications and surgical consideration
Prevention
References
51. Cardiac masses
Introduction
Subtypes of cardiac masses
References
Section IX. Special Problems/Diagnosis and Therapy
52. Evaluating murmurs, chest pain, and syncope
Murmurs
Chest pain
Syncope
References
53. Congestive heart failure
Definition
Epidemiology
Etiology
Pathophysiology
Categorization
Presentation
Evaluation
Management
Advanced heart failure
Mechanical circulatory support
Heart transplantation
Outcomes
References
54. Advanced cardiac therapies: Ventricular assist device and heart transplantation
Introduction
Mechanical circulatory support
Heart transplantation
References
55. Central nervous system sequelae of congenital heart disease
Introduction
Pathology
CNS imaging and monitoring
Risk factors for CNS injury and abnormality
Neuropsychological impairments
Psychosocial effects
Relationship of imaging to outcomes
Recommended screening, follow-up, and potential interventions
Summary
References
56. Pulmonary hypertension
Pulmonary vascular development
Pathophysiology of pulmonary hypertension
Genetic causes of pulmonary hypertension
Definition and clinical classification of pulmonary hypertension
Clinical presentation and evaluation of patients with pulmonary hypertension
Diagnostic evaluation of patients with pulmonary hypertension
Natural history and therapy for pulmonary hypertension
Therapy
Combination therapy
Summary
References
57. Adult congenital heart disease
Introduction
Physiology in flux
Ventricular vascular coupling
Pulmonary vascular disease
Heart failure and extracardiac organ dysfunction
Coping/lifelong palliative care
Living a meaningful life
Conclusions/gaps and future directions
References
58. Pregnancy and reproductive health in patients with congenital heart disease
Counseling women with congenital heart disease
Pregnancy-related cardiovascular hemodynamic changes
Maternal risk stratification variables
Medications during pregnancy and postpartum
Cardiovascular care during pregnancy
Cardiovascular care during delivery and postpartum
Specific congenital heart conditions
Right-sided heart lesions
Left-sided heart lesions
Complex lesions
Summary
References
59. The fontan circulation
Introduction
History of the fontan and its modifications
Physiology of the fontan circulation
Patient selection
Late complications
Risk factors and outcome prediction
Longitudinal fontan surveillance
A collaborative approach to discovery
References
Section X. Cardiac Surgery
60. Fundamentals of cardiopulmonary bypass for congenital heart surgery
Background/introduction
Basic components of the cardiopulmonary bypass circuit
Essential elements of the conduct of cardiopulmonary bypass
Physiologic management during cardiopulmonary bypass
Summary
References
61. Ventricular recruitment in patients with borderline ventricles
Introduction
Definition of borderline left or right heart
The borderline left heart
Staged left ventricular recruitment
Candidates for SLVR
Rationale for SLVR
Advantages of SLVR over primary biventricular repair
Timeline of events
SLVR diagnosis-specific strategies and considerations
Disadvantages of staged ventricular recruitment
Who should be considered candidates for SLVR?
When to convert to biventricular circulation?
The borderline right heart
Conclusion
References
62. Emerging techniques in cardiac surgery
Neonatal and infant surgery
Biventricular repair
Arterial switch operation for D-transposition of the great arteries
Surgery for interrupted aortic arch
Tetralogy of fallot
Complete atrioventricular septal defect
Management of the neonate and infant with single ventricle physiology
Congenital heart valve disease
New techniques
Clinical 3D modeling and surgical simulation
References
Section XI. Allied Disciplines
63. Sedation and anesthesia in cardiac procedures
Introduction
Defining levels of sedation and general anesthesia
Non-inhaled sedative and anesthetic agents
Muscle relaxants
Inhaled anesthetic agents
Preoperative assessment and preparation
Induction of sedation/anesthesia
Anesthesia for cardiac surgery
Anesthesia for cardiac catheterization
Magnetic resonance imaging and angiography
References
64. Cardiac intensive care unit
History
Newborn considerations
Preoperative care
Postoperative care
Management of the cyanotic patient
Diastolic dysfunction
Cardiovascular interactions with other organs
Managing acute pulmonary hypertension in the intensive care unit
Mechanical support of the circulation
Summary
Future directions
Acknowledgment
References
65. Contemporary pediatric cardiovascular nursing
Introduction
Nursing leadership and organizational structure
Patient safety and quality
Care coordination and APN-managed clinical programs
Professional development, advancement, and staff support
Conclusion
References
66. Translational research in pediatric cardiology
Introduction
Model systems
Understanding disease mechanisms
Improving patient management
Conclusion
References
Section XII. Future Direction
67. Innovation and areas for future research
Hepatic factor and pulmonary arteriovenous malformations
Improved localization of the conduction tissues during cardiac surgery
Ideal cardiovascular replacement devices for congenital heart disease
Healthcare delivery
Training in pediatric cardiology for the 21st century
References
Glossary of epononymous cardiac procedures
Index