Oxford Textbook of Neuroscience and Anaesthesiology

The perioperative care of individuals with neurologic compromise is critically important, yet it is only one dimension of the rich relationship between anaesthesiology and the neurosciences. The mechanism of everyday therapeutic interventions such as anaesthesia and analgesia is exciting neuroscience in its own right. At the new frontier of outcomes studies lies the question of how the perioperative period might impact the brain. For example, questions related to anaesthetic neurotoxicity, delirium, and cognitive dysfunction pose critical challenges for the field.

The Oxford Textbook in Neuroscience and Anaesthesiology addresses the exciting field of neuroanaesthesiology in a new and stimulating way. In twenty eight chapters, the neuroscientific basis of anaesthesiology, the full spectrum of clinical neuroanaesthesia, and the care of neurologic patients undergoing non-neurologic surgery are explored in one comprehensive textbook for the first time.

The first section considers the neural mechanisms of general anaesthetics, cerebral physiology, the neurobiology of pain, and more. The second section explores the care of patients with neurologic disease in the operating room or intensive care unit. These clinical chapters systematically treat the perioperative considerations of both brain and spine surgery, and provide introductions to neurocritical care and pediatric neuroanaesthesia. The final section outlines the care of neurologic patients undergoing non-neurologic surgery. It examines key connections of neurology and anaesthesiology, examining how conditions such as dementia, stroke, or epilepsy interface with the perioperative period.

Each chapter has been carefully crafted to be concise yet highly informative, reflecting the cutting edge of neuroscience and neuroanaesthesiology. This international textbook gathers the best available expertise of authors and leaders worldwide. Includes access to online-only content, including more than 20 cases and more than 90 questions that can be used in presentations and teaching sessions. By activating your unique access code, you can access and use the material.

Table of Contents

Section 1- Neuroscience in anaesthetic practice
1: Neural mechanisms of anaesthetics, Andrew McKinstry-Wu and Max Kelz
2: Intracranial pressure, Harald Stefanits, Andrea Reinprecht, and Klaus Ulrich Klein
3: Cerebral physiology, Stefan Bittner, Kerstin Göbel and Sven. G. Meuth
4: Monitoring anaesthetic depth, Michael Avidan and Jamie Sleigh
5: Autonomic nervous system, David B. Glick, Gerald Glick, and Erica J. Stein
6: Neuromuscular junction, Christiane G. Stäuble, Heidrun Fink, and Manfred Blobner
7: Principles of neuroprotection, Sophia C. Yi, Brian P. Lemkuil, and Piyush Patel
8: Neurotoxicity of general anaesthetics, Margaret K. Menzel Ellis and Ansgar Brambrink
9: Neurobiology of acute and chronic pain, Adrian Pichurko and Richard Harris
Section 2 - Clinical Neuroanaesthesia10: Neurologic emergencies  , Ross P. Martini and Ines P. Koerner
11: Neurophysiologic monitoring for neurosurgery, Antoun Koht, Laura B. Hemmer, J. Richard Toleikis, and Tod B. Sloan
12: Brain trauma, Anne Sebastiani and Kristin Engelhard
13: Supratentorial craniotomy for mass lesion, Shaun E. Gruenbaum and Federico Bilotta
14: Posterior fossa craniotomy, Tasha L. Welch and Jeffrey J. Pasternak
15: Cerebrovascular surgery, Deepak Sharma and David R. Wright
16: Interventional neuroradiology, Nathan Manning, Katherine M. Gelber, Michael Crimmins, Philip M. Meyers, and Eric J. Heyer
17: Pituitary and neuroendocrine surgery, Douglas A. Colquhoun and Edward C. Nemergut
18: Hydrocephalus and associated surgery, Paola Hurtado and Neus Fàbregas
19: Awake craniotomy, epilepsy and functional neurosurgery, Lashmi Venkatraghavan and Pirjo Manninen
20: Complex spine surgery, Ehab Farag and Zeyd Ebrahim
21: Spine trauma, Timur M. Urakov and Michael Y. Wang
22: Paediatric neurosurgery, Sulpicio G. Soriano and Craig D. McClain
23: Basics of neurocritical care, Magnus Teig and Martin Smith
Section 3 - Neurologic patients undergoing Non-neurologic surgery
24: Cerebrovascular disease, Robert Sanders and Corey Amlong
25: Dementia, Phillip E. Vlisides and Zhongcong Xie
26: Epilepsy, Adam D. Niesen, Adam K. Jacob, and Sandra L. Kopp
27: Parkinson s disease, M. Luke James and Ulrike Hoffmann
28: Major psychiatric disease, Laszlo Vutskits