Remington Education: Pharmaceutics

Remington Education: Pharmaceutics provides comprehensive yet concise coverage of all aspects of pharmaceutics. The first part of the book covers physico-chemical principles and highlights the importance of designing dosage forms that contain the appropriate dose, are stable, palatable, easily used by the patient and release drugs in a predictable fashion for absorption. The second part applies these formulation principles to the design of dosage forms used by each route of administration.

Each chapter advises on both the science of the delivery mechanism and appropriate use of that delivery system including patient counselling points. Each chapter features:

• Learning objectives
• Key points boxes
• Drug examples
• Illustrations
• Assessment questions
• Further reading and references

Shelley Chambers Fox is a registered pharmacist with experience in pharmacy practice as well as academia. Written for students who aspire to be practicing pharmacists the author has included numerous case studies and self assessment questions to enable the key concepts to be grasped more readily, while illustrating how the science can be applied to practice to make sure that drugs offer the intended benefit to the patient.

Table of Contents

1. Introduction to dosage form design
2. Intermolecular forces and the physical and pharmaceutical properties of drugs
3. Dispersed systems
4. Properties of solutions and manipulation of solubility
5. Chemical stability of drugs
6. Drug travel from dosage form to receptor
7. Bioavailability, bioequivalence and the Biopharmaceutical Classification System
8. Parenteral drug delivery
9. Delivery of biopharmaceuticals and the use of novel carrier systems
10. Drug delivery to the eye
11. Drug delivery from the oral cavity
12. Oral delivery of immediate release dosage forms
13. Oral delivery of modified release solid dosage forms
14. Rectal and vaginal drug delivery
15. Nasal drug delivery
16. Drug delivery to the lung and from the lung
17. Drug delivery to the skin
18. Transdermal dosage forms: drug delivery to the blood stream
Appendix
Answers to questions and cases