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2020 Updates Include:
- Management of opiate use disorder
- Multimodal pain management strategies for non-opiate analgesic agents and opiate-sparing drugs
- Current best practices for management of pain and sedation in critically ill patients such as the concept of analgosedation and comparisons of various sedative agents used for ICU sedation
- Newly published information on breakthrough oncology drugs approved as part of the FDA’s accelerated approval program
- Updating of pharmacogenomic considerations related to dosage adjustments (e.g., tamoxifen) or risk of sensitivity reactions (e.g., allopurinol, phenytoin or fosphenytoin)
- Expanded information on non-oncology off-label uses (e.g., mycophenolate in treating scleroderma; ketamine use in treatment-resistant depression)
- Addition of new therapies for the treatment of seizure disorders, including status epilepticus and intractable childhood epilepsy syndromes
- Use of Calcitonin Gene-Related Peptide (CGRP) antagonists in the preventive treatment of migraines
- Important changes in management of diabetes, including effects of SGLT2 inhibitors and GLP-1 agonists on cardiovascular risk reduction and beneficial effects on renal function
Special Feature: A discussion of recent evidence questioning aspirin’s role in primary prevention of cardiovascular events in most adults, including the American College of Cardiology and American Heart Association’s positions.