Regenerative Medicine

Regenerative Medicine is a fastly emerging interdisciplinary field of research and clinical therapies on the repair, replacement or regeneration of cells, tissues or organs in congenital or acquired disease. This new field of research and clinical development focussing on stem cell science and regenerative biology is just starting to be the most fascinating and controversial medical development at the dawn of the 21st century. Viewing the great expectations to restructure and regenerate tissue, organs or organisms the current attempts of scientist and physicians are still in an early phase of development. This new textbook on “Regenerative Medicine – from protocol to patient” is aiming to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. The international leading experts from four continents describe the latest scientific and clinical knowledge of the field of “Regenerative Medicine”. The process of translating science of laboratory protocols into therapies is explained in sections on basic science, clinical translation, regulatory, ethical and industrial issues. The textbook is aiming to give the student, the researcher, the health care professional, the physician, and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practised therapies in Regenerative Medicine.
Content Level » Research

Related subjects » Biomaterials - Biomedical Sciences - Cell Biology - Life Sciences - Molecular Medicine

Table of contents Foreword: Regenerative Medicine: A 21st century vision for medicine.- Chapter 1: History of regenerative medicine, Laurentiu Popescu, Part I: Biology of Tissue Regeneration: Chapter 2: Extracellular matrix and tissue regeneration, Prof. Dr. Yrjö T. Konttinen.- Chapter 3: Stem cells in tissue development, Hans R Schöler.- Chapter 4: Stem cells in tissue regeneration, Jonas Frisên.- Chapter 5: Stem cell niche, SI Nishikawa.- Part II Stem Cell Science and Technology: Chapter 6: Characterization and classification of stem cells, D Srivastava.- Chapter 7: Embryonic stem cells, J Hyllner.- Chapter 8: Induced Pluripotent stem cells, S Yamanaka.- Chapter 9: Spermatogonial and germ stem cells, Thomas Skutella.- Chapter 10: Hematopoeitic stem cells, Jon Frampton.- Chapter 11: Cardiovascular stem cells, Stefanie Dimmeler.- Chapter 12: Cardiac stem cells, Piero Anversa and Mauricio Capogrossi.- Chapter 13: Neural stem cells, Wieland B Huttner.- Chapter 14: Liver stem cells, Brigitte Vollmar.- Chapter 15: Gastrointestinal stem cells, N A Wright.- Chapter 16: Mesenchymal stem cells, Anthony D Ho.- Chapter 17: Musculosceletal stem cells, Gerjo Van Osch.- Part III Tissue Engineering, Biomaterials and Nanotechnology: Chapter 18: Vector technology and cell targeting, Brigitte Puetzer.- Chapter 19: Stem cell modification and reprogramming, A Terzic.- Chapter 20: Biodegradable materials, Eva Sykova and Andreas Lendlein.- Chapter 21: Functionalized Nanomaterials, James A Hubbell .- Chapter 22: Small Molecules, H Sadek, and EN Olson.- Chapter 23: Biointerface Technology, Alicia El Haj.- Chapter 24: Implant Bioengineering, Dominique Pioletti.- Chapter 25: Animal Models, Reinhold G. Erben.- 4 Part IV Regenerative Therapies: Charter 26: Pharmacology, Thomas Eschenhagen.- Charter 27: Blood, Katarina LeBlanc.- Charter 28: Immune System, H D Volk.- Chapter 29: Central Nervous System, Siddhartan Chandran.- Chapter 30: Spinal Cord and Peripheral Nervous System, Ivo Vanicky.- Chapter 31: Eye, T A Reh.- Chapter 32: Ear, R P Revoltella.- Charter 33: Dental, Kristina Arvidsson.- Chapter 34: Trachea, Paolo Macchiarini.- Chapter 35: Lung, M Rabinovitch.- Chapter 36: Vascular, Takayuki Asahara.- Chapter 37: Heart, Gustav Steinhoff and Bodo E. Strauer.- Chapter 38: Liver, Michael Ott.- Chapter 39: Kidney, H Haller.- Chapter 40: Gastrointestine, M P Manns.- Chapter 41: Endocrine, Moustapha Kassem.- Chapter 42: Skin, H G Machens.- Chapter 43: Bone, Dietmar W Hutmacher, Chapter 44: Cartilage, Frank Luyten and Georg Duda.- Chapter 45: Muscle and tendons, T. Mittlmeier and P. Vogt.- Part V Regulation and Ethics: Chapter 46: Approval of advanced therapies: FDA and EMEA regulations, Andreas Cichutek and Gudrun Tiedemann.- Chapter 47: Ethical guidelines and legal control: an international mapping, Greg Becker and Anna Grabinski.- Chapter 48: Guidelines for GMP stem cell production, Hans D Kleine and Peter Sartipy.- Chapter 49: Developmental guidelines for stem cell therapies, Chris Mason.- Chapter 50: Patient propositions, Robert Klein.- Index.