Developmental Origins of Health and Disease

Συγγραφείς: Peter Gluckman , Mark Hanson
ISBN: 9780521847438
Εκδότης: Cambridge University Press
Σελίδες: 542
Έτος Έκδοσης: 2006

Σύμφωνα με 0 αξιολογήσεις. - Γράψτε μια αξιολόγηση

214,00€

238,00€

Χωρίς ΦΠΑ: 201,89€

Ποσότητα

Προσθήκη στο καλάθι

Επιθυμητό Σύγκριση

Περιγραφή
Αξιολογήσεις

This landmark publication provides the first definitive account of how and why subtle influences on the fetus and during early life can have such profound consequences for adult health and diseases. Although the epidemiological evidence for this link has long proved compelling, it is only much more recently that the scientific and physiological basis for this has begun to be studied in depth and fully understood. This compilation, written by many of the world's leading experts in this exciting field, summarizes these scientific and clinical advances. The link between early development and the onset of many chronic diseases such as coronary heart disease, diabetes and osteoporosis, also raises important public health issues. Another fascinating theme in the book concerns evolutionary developmental biology and how the 'evo-devo' debate can cast light on these concepts. Clinicians and scientists alike will all learn a lot about this exciting and emerging field.

Links early development to the onset of many chronic diseases such as coronary heart disease, diabetes and osteoporosis
Explains concepts, possible mechanisms, outcomes and public health consequences
A definitive account of a rapidly emerging area
Authors of the The Fetal Matrix: Evolution, Development and Disease

1. The developmental origins of health and disease: an overview
2. The 'developmental origins' hypothesis: epidemiology
3. The conceptual basis for the developmental origins of health and disease
4. The periconceptional and embryonic period
5. Epigenetic mechanisms
6. A mitochondrial component of developmental programming
7. Role of exposure to environmental chemicals in developmental origins of health and disease
8. Maternal nutrition and fetal growth and development
9. Placental mechanisms and developmental origins of health and disease
10. Control of fetal metabolism: relevance to developmental origins of health and disease
11. Lipid metabolism: relevance to developmental origins of health and disease
12. Prenatal hypoxia: relevance to developmental origins of health and disease
13. The fetal hypothalamic-pituitary-adrenal axis: relevance to developmental origins of health and disease
14. Perinatal influences on the endocrine and metabolic axes during childhood
15. Developmental origins of health and disease: relevance of patterns of growth
16. The developmental environment and the endocrine pancreas
17. The develop
28. The developmental environment and the origins of neurological disorders mental environment and insulin resistance
18. The developmental environment and the development of obesity
19. The developmental environment and its role in the metabolic syndrome
20. Programming the cardiovascular system
21. The role of vascular dysfunction in developmental
22. The developmental environment and atherogenesis origins of health and disease: evidence from studies in man and animals
23. The developmental environment, renal function and disease
24. The developmental environment: effect on fluid and electrolyte homeostasis
25. The developmental environment: effects on lung structure and function
26. Developmental origins of asthma and related allergic disorders
27. The developmental environment: Influences on subsequent cognitive function and behaviour
28. The developmental environment and the origins of neurological disorders
29. The developmental environment: clinical perspectives on effects on the musculoskeletal system
30. The developmental environment: experimental perspectives on skeletal development
31. The developmental environment and the early origins of cancer
32. The developmental environment: implications for aging and lifespan
33. Developmental origins of health and disease: implications for primary intervention for cardiovascular and metabolic disease
34. Developmental origins of health and disease: public health perspectives
35. Developmental origins of health and disease: implications for developing countries
36. Developmental origins of health and disease: ethical and social considerations.