Diagnostic Atlas of Renal Pathology, 3rd Edition

• A new chapter describing a logical approach to differential diagnosis.

 

• New insights into pathogenesis and classification of diseases.

 

 

• New coverage of aging and the kidney, endemic diseases, transplant, lupus-related kidney diseases, Mesoamerican nephropathy, ApolL1-related nephropathies, C3 glomerulopathies, and thrombotic microangiopathies.

 

 

• Recent results of consensus conferences on vasculitides and renal neoplasia.

 

By Agnes B. Fogo, MD, Professor of Pathology, Medicine and Pediatrics, Director, Renal Electron Microscopy laboratory, Vanderbilt University Medical Center, Nashville, Tennessee, USA and Michael Kashgarian, MD, Professor Emeritus of Pathology and Molecular, Cellular, and Developmental Biology; Department of Pathology, Yale University, New Haven, Connecticut, USA

Table of Contents:

1. Approach to Diagnosis of the Kidney Biopsy

2. Normal Growth and Maturation

3. Glomerular Diseases

PRIMARY GLOMERULAR DISEASES

Glomerular Diseases That Cause Nephrotic Syndrome: Non-Immune Complex

Glomerular Diseases That Cause Nephrotic/Nephritic Syndrome: Complement Related

Glomerular Diseases That Cause Nephrotic Syndrome: Immune Complex

Glomerular Diseases That Cause Hematuria or Nephritic Syndrome: Immune Complex

SECONDARY GLOMERULAR DISEASES

Diseases Associated with Nephrotic Syndrome

Diseases Associated with Nephritic Syndrome or RPGN: Immune Mediated

Diseases Associated with the Nephritic Syndrome or RPGN: Pauci-Immune- or Non-Immune-Mediated

Diseases with Abnormal Basement Membranes

Glomerular Involvement with Bacterial Infections

4. Vascular Diseases

Diabetic Nephropathy

Thrombotic Microangiopathy/ Thrombotic Thrombocytopenic Purpura

Scleroderma

Antiphospholipid Antibody Disease

Preeclampsia and Eclampsia

Fibromuscular Dysplasia

Arterionephrosclerosis

Accelerated/Malignant Hypertension

Atheroemboli

5. Tubulointerstitial Diseases

Introduction

Infections of the Kidney

Acute Pyelonephritis

Chronic Pyelonephritis and Reflux Nephropathy

Xanthogranulomatous Pyelonephritis

Malakoplakia

Acute Tubulointerstitial Nephritis - Viral Infection

Acute Tubulointerstitial Nephritis-Drug-Related

Tubulointerstitial Nephritis With Uveitis

Anti-TBM Antibody Nephritis

IgG4-Related Tubulointerstitial Nephritis

Interstitial Nephritis of Sjogren Syndrome

Sarcoidosis

Acute Kidney Injury/Acute Tubular Necrosis

Warfarin-Induced Acute Kidney Injury/ Anticoagulant- Related Nephropathy

Heavy Metal Nephropathy (Lead and Cadmium Nephropathy)

Analgesic Nephropathy and Papillary Necrosis

Light Chain Cast Nephropathy and Tubulopathy

Tubular Crystallopathies

Lithium Nephropathy

Aristolochic Acid Nephropathy

6. Endemic Nephropathies

Introduction

Aristolochic Acid Nephropathy

Other Endemic Fibrosing Nephropathies

7. Chronic Kidney Disease

Introduction

Age-Related Sclerosis

Glomerular vs. Tubulointerstitial vs. Vascular Disease

Segmental Glomerulosclerosis: Primary vs. Secondary

8. Renal Transplantation

Introduction

Evaluation of Donor Kidneys

Antibody-Mediated Rejection

Chronic Active Antibody- Mediated Rejection and Transplant Glomerulopathy

Acute T Cell-Mediated Rejection

Chronic T Cell-Mediated Rejection

Interstitial Fibrosis and Tubular Atrophy

Cyclosporin/Tacrolimus Nephrotoxicity

Sirolimus (Rapamycin) Nephrotoxicity

Posttransplant Lymphoproliferative Disease

Viral Infections

Recurrent Renal Disease

9. Cystic Diseases of the Kidney

Introduction

Autosomal Dominant Polycystic Kidney Disease

Autosomal Recessive Polycystic Kidney Disease

Medullary Cystic Diseases

Medullary Sponge Kidney

Acquired Cystic Disease

Cystic Renal Dysplasia

10. Renal Neoplasia

Introduction

Renal Neoplasms

Nephroblastoma (Wilms Tumor)

Renal Angiomyolipoma

Urothelial (Transitional Cell) Carcinoma of the Renal Pelvis