Assessing Human Exposure to Key Chemical Carcinogens. Diagnostic Approaches and Interpretation

This book introduces an effective, affordable, non-invasive, and quick method to detect exposure to dangerous chemical carcinogens, which cause life-threatening conditions like cardiovascular, endocrine, neurological, hematological, dermatological, and malignant diseases. Nearly 20 million people are diagnosed with cancer annually, with almost 10 million deaths. While eliminating carcinogens completely is impossible, improving detection and monitoring—especially through specialized urine analysis—can help define preventive measures to lower carcinogen levels in the body.

The chemical carcinogens discussed have been used for decades without proper evaluation of their health effects, costing millions of lives. Considering the long-term health impacts of current products is critical. Early detection is crucial as most carcinogens have cumulative effects. Identifying urinary markers of exposure can help detect, eliminate, or reduce sources of carcinogens, advancing preventive oncology.

The book focuses on Group 1 chemical carcinogens classified by the International Agency for Research on Cancer (IARC). The described methods are highly effective, affordable, and applicable in any location with HPLC (High-Performance Liquid Chromatography) and ICP (Inductively Coupled Plasma) devices. They are non-invasive, requiring only urine samples, quick, and inexpensive.

This volume aims to develop, improve, and implement screening methods for malignant diseases. It supports medical professionals in interpreting HPLC and ICP urinary analyses and providing guidance on reducing or avoiding carcinogen exposure. In some cases, doctors may identify sources of exposure and inform authorities to address and eliminate these hazards.

• Supports readers to avoid or reduce own exposure to the most dangerous chemical carcinogens
• Offers critical questions for doctors to evaluate a patient’s risk of contamination
• Inspires readers to develop new skills through examples of applications which have translated research into practice