Handbook of Pharmaceutical Granulation Technology 4E

Table of Contents

Preface

About the Editor

List of Contributors

Chapter 1 Introduction, Dilip M. Parikh

Chapter 2 Theory of Granulation: An Engineering Perspective, Bryan J. Ennis, Michael Winn, Brandon Ennis, Naseem Jibrin

Chapter 3 Drug Substance and Excipient Characterization, Parind M. Desai, Lai Wah Chan, Paul Wan Sia Heng 

Chapter 4 Binders in Pharmaceutical Granulation, Thomas Durig, Kapish Karan

Chapter 5 Excipients and their Attributes in Granulation, Anthony E. Carpanzano

Chapter 6 Spray Drying and Pharmaceutical Applications, Metin Celik, Pavan Muttil, Gulsilan Binzet and Susan C. Wendell

Chapter 7 Emerging Technologies for Particle Engineering, Dilip M. Parikh

Chapter 8 Roller Compaction Technology, Ronald Miller, Vishwas Nesarikar

Chapter 9 Advances in Wet Granulation of Modern Drugs, Bing Xun TAN, Wen Chin FOO, Keat Theng CHOW, Rajeev GOKHALE 

Chapter 10 Fluid Bed Processing, Dilip M. Parikh

Chapter 11 Single Pot Processing, Griet Van Vaerenbergh, Harald Stahl

Chapter 12 Extrusion/Spheronization as a Granulation Technique, David F. Erkoboni

Chapter 13 Continuous Granulation, Chris Vervaet, Thomas De Beer, Valerie Vanhoorne

Chapter 14 Effervescent Granulation, Guia Bertuzzi

Chapter 15 Granulation of Plant Products and Nutraceuticals, Dilip M. Parikh

Chapter 16 Granulation Approaches for Modified Release Products, Neelima Phadnis, Sree Nadkarni

Chapter 17 Granulation of Poorly Water-Soluble Drugs, Albert W. Brzeczko, Firas El Saleh, Hibreniguss Terefe

Chapter 18 Granulation and Production Approaches of Orally Disintegrating Tablets, Tansel COMOGLU, Fatemeh BAHADORI

Chapter 19 Melt Granulation, Shana Van de Steene, Valérie Vanhoorne, Chris Vervaet, Thomas De Beer

Chapter 20 Sizing of Granulation, Gurvinder Singh Rekhi, Richard Sidwell             

Chapter 21 Granulation Characterization, Cecil W. Propst

Chapter 22 Bioavailability and Granule Properties, Sunil S. Jambhekar

Chapter 23 Granulation Process Modeling, Ian T. Cameron, Fu Y. Wang

Chapter 24 Scale-Up Considerations in Granulation, Yinghe He, Lian X. Liu, James Lister, Defne Kayrak-Talak

Chapter 25 Advances in Process Controls and End-Point Determination, Kevin A. Macias, M. Teresa Carvajal  

Chapter 26 Use of Artificial Intelligence and Expert Systems in Pharmaceutical Applications, Metin Çelik

Chapter 27 Regulatory Issues in Granulation: Leading Next Generation Manufacturing, Prasad Kanneganti

Chapter 28 QbD and PAT in Granulation, Shivang Chaudhary

Editor(s)

Biography

Dilip M. Parikh is President, DPharma Group Inc., Ellicott City, Maryland, USA. As a Chemical and pharmaceutical engineer, he has more than 45 years of experience in product developments and manufacturing, process engineering, operational management of various pharmaceutical facilities in Canada and the USA. He is an invited speaker globally on various solid dosage manufacturing technologies and troubleshooting, process optimization strategies, regulatory remediation, and PAT & QbD implementation strategies. The author of many scientific journal articles, book chapters, and the editor of first, the second and third edition of Handbook of Pharmaceutical Granulation Technology.