Pediatric Pathology of Hematopoietic and Histiocytic Disorders

The presentation of hematolymphoid and histiocytic diseases can vary widely between children and adults as can age-related differential diagnoses and the consequences of treatment. Providing up to date information and classification for diseases across the hematopoietic, lymphoid and histiocytic systems, the book also covers morphologic, immunophenotypic, cytogenetic, and molecular genetic features of routine and diagnostically challenging disorders in pediatric patients. Over 200 high-quality colour illustrations aid accurate diagnosis and correct interpretations when evaluating peripheral blood, bone marrow, lymph nodes and other tissues specimens. This comprehensive yet practical guide also discusses useful ancillary tests and introduces newly recognised entities identified in the current literature, such as GATA-2 haploinsufficiency, B-ALL with DUX4-IGH and ERG deletion, and ALK-positive histiocytosis. An online version of the book with expandable figures can be accessed on Cambridge Core, via the code printed on the inside of the cover.

• Contains over 200 high-quality colour images that are fully annotated to aid accurate diagnosis and correct interpretations when evaluating peripheral blood, bone marrow, lymph node and other tissue specimens.
• Approaches the subject from a practical standpoint, providing quick but authoritative answers to clinicians who may encounter patients with these diseases in their everyday clinical practice.
• Readers can gain full HTML access of the whole book with expandable figures via a scratch-off code inside the cover.