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Hepato-Pancreato-Biliary Malignancies Diagnosis and Treatment in the 21st Century

 Hepato-Pancreato-Biliary Malignancies  Diagnosis and Treatment in the 21st Century
Hepato-Pancreato-Biliary Malignancies Diagnosis and Treatment in the 21st Century
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About this book

Hepato-Pancreato-Biliary cancers are increasing in incidence, with pancreatic cancer now accounting for the third most cancer deaths in the United States.  Typically these malignancies, as a group, are managed by the same key providers comprising a multidisciplinary team.

 

This book is intended to provide a comprehensive review of the current knowledge in the field of hepato-pancreato-biliary malignancies, focusing on the practical and clinical care of patients.  We take the approach of combining the collective expertise of an interventional gastroenterologist and a hepato-pancreato-biliary surgeon to provide the readers with accurate, succinct, and pragmatic information needed to formulate the most appropriate treatment plan for their patients with the aim of the best possible outcome.  

 

Managing patients with these cancers continues to be challenging because of continued dismal survival rates. Each section in this text is written by experts in their respective field, summarizing the most state-of-the-art, contemporary diagnostic and therapeutic tools available in the field. We believe this book will prove to be an invaluable, comprehensive resource for all members of the multidisciplinary team caring for patients with hepato-pancreato-biliary malignancies.

Table of contents (46 entries)

  1. Front Matter

    Pages i-xxii
  2. Hepatic Malignancies

    1. Front Matter

      Pages 1-1
    2. Approach to the Patient with a Solid Liver Mass

      • Eyob Feyssa, Santiago J. Munoz
      Pages 3-26
    3. Diagnosis and Evaluation of Hepatocellular Carcinoma

      • Naemat Sandhu, Simona Rossi
      Pages 27-48
    4. Hepatocellular Carcinoma Pathology

      • Ronald Miick, Corrado Minimo, Alessandro Bombonati
      Pages 49-86
    5. Metabolic Syndrome and Liver Cancer

      • Ariel Jaffe, Mario Strazzabosco
      Pages 87-104
    6. Reducing the Risk of and Screening for Liver Cancer

      • Simranjit Bedi, Ashley Davis, Victor Navarro
      Pages 105-123
    7. Medical Management of Hepatocellular Carcinoma

      • Ahmad Safra
      Pages 125-130
    8. Surgical Management of Hepatocellular Carcinoma

      • Duilio Pagano, Giuseppe Mamone, Sergio Calamia, Salvatore Gruttadauria
      Pages 131-145
    9. IR Liver-Directed Therapies for HCC

      • Ajay Choudhri
      Pages 147-158
    10. Clinical Presentation, Diagnosis, and Management of Uncommon Liver Tumors

      • Elizabeth Richardson, Scott Fink, Jessica Fried
      Pages 159-181
    11. Epidemiology, Pathogenesis, and Prognosis of Uncommon Liver Tumors

      • Elizabeth Richardson, Scott Fink
      Pages 183-195
    12. Treatment of Liver Metastases from Colorectal Cancer

      • Richard S. Hoehn, Samer T. Tohme, David A. Geller
      Pages 197-212
    13. Treatment of Isolated Liver Metastasis from Non-colorectal Cancer

      • John B. Martinie, Benjamin M. Motz, Jordan N. Robinson
      Pages 213-234
  3. Bile Duct Malignancies

    1. Front Matter

      Pages 235-235
    2. Diagnosis and Evaluation of Cholangiocarcinoma

      • Tina Boortalary, David Loren
      Pages 237-264
    3. Cholangiocarcinoma: Epidemiology, Pathogenesis, and Prognosis

      • Yunseok Namn, Juan Carlos Bucobo
      Pages 265-293
    4. The Pathophysiology and Pathology of Intrahepatic and Extrahepatic Cholangiocarcinomas

      • Cindy Wang, Namrata Setia
      Pages 295-306
    5. Nonsurgical Management of Cholangiocarcinoma

      • Michael J. Breen, Osman S. Ahmed, Joshua Owen, Chih-Yi Liao
      Pages 307-323
    6. Surgical Treatment of Intrahepatic Cholangiocarcinoma

      • Ki-Hun Kim, Jeong-Ik Park
      Pages 325-331
      1. Bile Duct Malignancies

        1. Endoscopic Palliative Management of Cholangiocarcinoma

          • Sanmeet Singh, Ajaypal Singh, Uzma D. Siddiqui
          Pages 333-345
        2. Rare Tumors of the Bile Ducts

          • Earl V. Campbell III, Priya Jamidar
          Pages 347-361
      2. Gallbladder Cancer

        1. Front Matter

          Pages 363-363
        2. Diagnosis and Evaluation of Gallbladder Cancer

          • Unal Aydin
          Pages 365-371
        3. Pathogenesis, Epidemiology, and Prognosis of Gallbladder Cancer

          • Lauren Margetich
          Pages 373-378
        4. Pathology of Gallbladder Carcinoma

          • Namrata Setia, Katherine E. Boylan
          Pages 379-386
        5. Nonsurgical Management of Gallbladder Cancer

          • Neel Gandhi, Timothy Chen
          Pages 387-394
      3. Pancreatic Malignancies

        1. Front Matter

          Pages 395-395
        2. Approach to the Patient with a Pancreatic Mass

          • Daniel Lew, Shreyas Srinivas, Karl Kwok
          Pages 397-413
        3. Evaluation and Management of the Patient with a Pancreatic Cyst

          • Suut Göktürk, Thiruvengadam Muniraj, Harry R. Aslanian
          Pages 415-430
        4. Diagnosis and Evaluation of Pancreatic and Periampullary Adenocarcinoma

          • Daniel Lew, Karl Kwok
          Pages 431-459
        5. Pathogenesis, Epidemiology, and Prognosis of Pancreatic Adenocarcinomas

          • Katherine Kim, Srinivas Gaddam, Quin Liu
          Pages 461-481
        6. Pathology of Pancreatic Ductal Adenocarcinoma

          • Xuebin Yang, Krister Jones, Guoli Chen
          Pages 483-517
        7. Reducing the Risk of and Screening for Pancreatic Cancer

          • Shivangi Kothari, Vivek Kaul, Truptesh H. Kothari
          Pages 519-533
        8. Nonsurgical Management of Pancreatic Adenocarcinoma

          • H. Liang, S. Williamson
          Pages 535-556
        9. Surgical Management of Pancreatic Adenocarcinoma

          • Antonio Di Carlo, Meredith Gunder, Cataldo Doria
          Pages 557-568
        10. Intraoperative Radiation Treatment

          • Yurie Sekigami, Theodoros Michelakos, Cristina Ferrone
          Pages 569-578
        11. Palliative Endoscopic Therapy of Pancreatic Duct Adenocarcinoma (PDAC)

          • Nicholas G. Brown, Amrita Sethi
          Pages 579-595
        12. Diagnosis and Management of Pancreatic Neuroendocrine Tumors and Other Rare Pancreatic Neoplasms

          • Andrew Foong, James Buxbaum
          Pages 597-622
        13. Epidemiology, Pathogenesis, and Prognosis of Pancreatic Neuroendocrine Tumors

          • Tara Keihanian, Mohamed Othman
          Pages 623-637
          1. Pancreatic Malignancies

            1. Pathology of Pancreatic Neuroendocrine Tumors

              • Filippo Borri, Rita Bonfiglio, Martina Mandarano
              Pages 639-681
            2. Non-surgical Management of Pancreatic Neuroendocrine Tumors (PNETs)

              • Abhishek Chouthai, Michael Makar, Avik Sarkar
              Pages 683-709
            3. Surgical Management of Pancreatic Neuroendocrine Tumors (PNET)

              • Candace Gonzalez, Anthony DeSantis, Meagan Read, Andreas Karachristos
              Pages 711-733
            4. Emerging Endoscopic Therapies for Pancreatic Neuroendocrine Tumors

              • Thomas E. Kowalski, Brianna J. Shinn
              Pages 735-744
          2. Emerging And Future Trends In Managing Hepatobiliary And Pancreatic Malignancies

            1. Front Matter

              Pages 745-745
            2. Molecular and Genetic Profiling for the Diagnosis and Therapy of Hepatobiliary and Pancreatic Malignancies

              • H. Liang, R. Remstein, D. Lewis
              Pages 747-759
            3. Personalized Medicine for Patients with Liver, Biliary Tract, and Pancreatic Cancer

              • Monica Valente, Alessia Covre, Anna Maria Di Giacomo, Michele Maio
              Pages 761-776
            4. The Role of Robotic Surgery in Treating Hepatobiliary and Pancreatic Malignancies

              • Anusak Yiengpruksawan
              Pages 777-785
            5. The Multidisciplinary Approach to Managing Hepatobiliary and Pancreatic Malignancies and Its Importance

              • V. Kostaras, S. Lakkasani
              Pages 787-812
            6. The Role of the Palliative Care Team in the Management of Hepatobiliary and Pancreatic Malignancies

              • Carolyn Gaukler
              Pages 813-826
            7. Spiritual Thinking and Surgery

              • Ignazio R. Marino
              Pages 827-834
            8. Integrative Medicine and Hepatobiliary and Pancreatic Cancer: What to Expect

              • Chloe Hriso, Anthony Bazzan, Daniel Monti, Andrew Newberg
              Pages 835-846
          3. Back Matter

            Pages 847-865

            About the editors

            Dr. Cataldo Doria is an internationally renowned surgeon who specializes in surgical treatments of the liver, pancreas, and bile duct. Dr. Doria spent a quarter of a century in academic medicine, at University of Pittsburg Medical Center in Pittsburgh first, and at Thomas Jefferson University Hospital in Philadelphia later.

            Dr. Doria was a major contributor to the start-up of the European Medical Division of the University of Pittsburgh Medical Center, which resulted in a cultural and scientific cooperative agreement between the University of Pittsburgh and the University of Palermo - Italy. This partnership led to the development of the Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione,(IsMeTT), a health care delivery system that serves the entire Mediterranean Basin and specializes in solid organ transplantation and cancer care.  From 1999 to 2003, Dr Doria, was the clinical leader of IsMeTT. 

            At Thomas Jefferson University Hospital in Philadelphia, PA, he served as the surgical director of the Sidney Kimmel Cancer Center – Jefferson Liver Tumor Center at Jefferson Medical College, and director of the Jefferson Transplant Institute.  During his 15 years tenure at Jefferson Dr. Doria resurrected, first hand, a program in agony and made it one of the best in the Country for volume, outcome, patient satisfaction, and innovative research.

            Dr. Doria received his medical degree at University of Perugia School of Medicine in Italy, where he also completed his internship and residency. He completed a research fellowship and a clinical fellowship in multi-organ transplant surgery at the Pittsburgh Transplantation Institute, part of the University of Pittsburgh School of Medicine in Pittsburgh, PA. Dr. Doria is a PhD in biotechnology and transplant immunology; he is, also, one of the few Doctors worldwide that successfully completed a clinical fellowship in living donor liver transplantation at the Organ Transplantation Center, part of Asan Medical Center in Seoul, South Korea.  Dr. Doria is a 2016 Temple Fox School of Business graduate.

            Dr. Doria is currently the Medical Director of the Cancer Center at Capital Health in Pennington, NJ. During the first three years of his tenure at Capital Health, under Dr. Doria’s leadership, the net revenue of the cancer center increased in excess of 25% every year.

            Dr. Doria has pioneered new techniques for conditions that were once considered untreatable. He has helped developing and introducing a number of innovative procedures to treat cancer patients that were not previously available, including bloodless liver surgery, ex-vivo liver resection with liver auto-transplantation and robotic-assisted hepato-pancreato-biliary surgery. He completed the first robotic assisted Whipple procedure in the State of New Jersey.


            Dr. Jason N. Rogart
            As an interventional gastroenterologist and therapeutic endoscopist, Dr. Rogart performs the latest and most advanced procedures for the testing and non-surgical treatment of pancreato-biliary disorders and malignancies. He is nationally recognized as an expert in the fields of endoscopic ultrasound (EUS), endoscopic retrograde cholangiopancreatography (ERCP), pseudocyst drainage, enteral stent placement, advanced endoscopic imaging, as well as numerous other procedures which help in the care of patients with gastrointestinal malignancies. 

             

            Dr. Rogart received his medical degree from Brown Medical School and completed his internship and residency at Yale University in the Department of Internal Medicine at Yale-New Haven Hospital, where he was also Chief Resident. He completed his fellowship training in digestive diseases at Yale University/Yale-New Haven Hospital and subsequently was an Advanced Endoscopy fellow in the Division of Gastroenterology & Hepatology at Thomas Jefferson University Hospital in Philadelphia, PA. Dr. Rogart holds an academic appointment at Rutgers—Robert Wood Johnson Medical School. 

             

            Dr. Rogart has published numerous original research articles and chapters in various national and international journals and resource textbooks. He has also been an invited speaker and faculty member at numerous locoregional and national conferences, including Digestive Diseases Week, the American Society for Gastrointestinal Endoscopy, the American College of Gastroenterology and the Society of Gastrointestinal Nurses and Associates. He is a reviewer for several national and international clinical publications.

             

            In 2014, Dr. Rogart was awarded the honorable distinction of “Fellow” in the American Society of Gastrointestinal Endoscopy (FASGE) for his lifelong contributions to the field of GI endoscopy and his dedication to patient care, research, teaching, and service.


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Ετικέτες: Surgery , Radiology