Colorectal Cancer From Pathogenesis to Precision Medicine

This concise text examines the contribution of genetic research to clinical practice in colorectal cancer. It delves into the underlying molecular mechanisms and the genetic and environmental factors contributing to colorectal cancer, as well as into advances in personalized therapies, targeted interventions, and biomarker-based approaches. By providing a comprehensive overview of the subject, the book aims to bridge the gap between scientific research and clinical practice, offering valuable insights to researchers, clinicians, and healthcare professionals dedicated to combating colorectal cancer and improving patient outcomes.

• Unites scientific discovery to clinical practice
• Offers a practical resource for the multidisciplinary team treating colorectal cancer patients
• Presents the state of the art in clinical management

CONTENTS

1. Introduction To Colorectal Cancer - Sonia Tamanna, Taslimul Jannat, and Anass M Abbas. 2. Epidemiology And Risk Factors of Colorectal Cancer - Saliha Rizvi, Sanchita Srivastava, Haider Ali Rizvi, Rizwan Askari, Syed Tasleem Raza, and Farzana Mahdi. 3. Molecular Pathogenesis of Colorectal Cancer - Rizwan Ahamad, Sadma Parveen, Abu Safana Biswas, and Ayman AM Alameen. 4. Genetic Mutations and Inherited Syndromes - Saliha Rizvi, Naseem Fatima, Farheen Khan, Syed Tasleem Raza, Gowhar Rashid, and Farzana Mahdi. 5. Screening And Early Detection Strategies - Mohammad Taghi Ahady, Marjan Assefi, Ananya Chakraborty, Manar G. Shalabi, and Wael Hafez. 6. Diagnostic Techniques and Imaging Modalities - Mohd Amir Shafeeque, Dilshad Ahmad, Satya N. Sankwar, Noorin Zaidi, and Zainab Siddiqui. 7. Adjuvants and Neoadjuvant Therapies in the Treatment of Colorectal Cancer - Subhajit Karmakar, Atharva Anand Mahajan, and Subhrojyoti Ghosh. 8. Targeted therapies in Colorectal cancer - Shivang Saxena, Palakodeti Sreekari, Mohit Thakral, and Ashwin Kotnis. 9. Immunotherapy and Immune Checkpoint Inhibitors - Yamna Khurshid and Kinza Rafi. 10. Personalized Medicine and Precision Oncology in Colorectal Cancer - Roy Rillera Marzo. 11. Biomarkers for diagnosis, prognosis and treatment response - Wasan A.M. Al Taie, May K. Ismail, Arwa Alnahdi, Eslam ElNebrisi, Eman Hassan Ibrahim, and Saba Z. Al- Abachi. 12. Survivorship and Supportive Care - Praveen Halagali, Vamshi Krishna Tippavajhala, Himanshu Sharma, and Harpreet Singh. 13. Colorectal Cancer in distinct demographics: Addressing the challenges in young adults and the elderly - Roy Rillera Marzo. 14. Future Perspective and Emerging Therapies - SM Mahfooz Hasan, Mohammad Waseem, Satya N. Sankwar, and Zainab Siddiqui.