International Compendium of Movement Disorders

A comprehensive and multidisciplinary guide to understanding and treating a wide range of movement disorders, including parkinsonisms, tremor, tics, dystonia, chorea, ballism and myoclonus. Split into five sections, the first is a basic introduction to the subject, covering the principles of human motor behavior and functional anatomy. The next three sections discuss movement disorders in depth, grouped into hypokinetic, hyperkinetic, and dyscoordinative and otherwise inappropriate motor behaviours, covering clinical manifestations, diagnostic features and therapeutic strategies. The last section explores the different ways of objectifying selected behavioral movement disorders. 90 videos, hosted online, and over 200 figures illustrate the concepts covered in the book, offering a visual reference for the disorders discussed. This compendium offers an essential tool to recognize, interpret and understand the clinical manifestations and underlying disorders of neurological movement disorders, and to select the best therapeutic strategies.

• 90 videos and over 200 colour figures illustrate the concepts covered in the book and help readers connect to the material
• Split into five sections, allowing readers to quickly access necessary information and enabling clinicians to concentrate on their desired area of knowledge
• Written and edited by a team of global experts, bringing diverse experience and knowledge bases to the book, with specialties encompassing rehabilitation medicine, neurosurgery and psychiatry
• Includes access to a HTML version of the text on Cambridge Core, where you can view inline videos and high-resolution images

CONTENTS

Section 1. Basic Introduction:1. Behavior: Basic Principles and Behavioral Movement Disorders
2. The Basal Ganglia
3. The role of the Cerebellum
4. Neuropathological Overview of Neurodegenerative disorders
5. Genetic Models of Movement Disorders
6. Mitochondrial Movement Disorders
7. Metabolic Movement Disorders
8. Auto-Immune Movement Disorders
9. Pediatric Movement Disorders
10. Neuro-Ophthalmology in Movement Disorders
11. Parkinson’s Disease
Section 2. Hypokinetic Movement Disorders:
12. Autonomic Dysfunction in Parkinson’s Disease
13. Neuropsychiatric Manifestations in Parkinson Disease
14. Sleep-Wake Disorders in PD
15. Neuronal activity in the basal ganglia and thalamus in patients with Parkinson’s disease
16. Pathology in PD
17. Diagnosis of PD
18. Prodromal Manifestations of PD
19. Biomarkers in PD
20. Allied Health Strategies in PD
21. Regenerative Strategies in PD
22. Conventional Pharmacotherapy in PD
23. Continuous Dopaminergic Stimulation in PD
24. Pipeline of Pharmacotherapy in PD
25. Noninvasive brain stimulation for the treatment of Parkinson’s disease
26. Deep Brain Stimulation in PD
27. Focused Ultrasound in PD
28. Dementia with Lewy Bodies
29. Genetic Parkinsonisms
30. Multiple System Atrophy
31. Progressive Supranuclear Palsy
32. Corticobasal Degeneration and Corticobasal Syndrome
33. Other Tau-Related Parkinsonisms
34. Vascular Parkinsonism
35. Illicit Drug-Induced Parkinsonism
Section 3. Hyperkinetic Movement Disorders:
36. Primary Dystonia
37. Secondary Dystonia
38. Treatment of Dystonia
39. Primary and Secondary Tremors
40. Pathophysiology in Tremor
41. Treatment of Tremor
42. Myoclonus
43. Chorea
44. Ballism
45. Gilles de la Tourette Syndrome and Other Tics
Section 4. Dyscoordinative and Otherwise Inappropriate Motor Behaviors:
46. Ataxia
47. Treatable Hereditary Cerebellar Ataxias
48. Gait and Balance Disorders
49. Episodic-Paroxysmal Movement Disorders
50. Sleep-Related Movement Disorders
51. Drug-Induced Movement Disorders
52. Psychiatric Movement Disorders
53. Functional Movement Disorders
Section 5. Objectifying Movement Disorders:
54. The Art of Phenotyping
55. Motor and Functional Scales for Movement Disorders
56. Wearables
57. Clinical Neurophysiology in Movement Disorders
58. Structural Imaging
59. Functional Imaging
Video fragments
Acronyms and abbreviations
Index.