Polycystic Ovary Syndrome, 3E

Polycystic ovary syndrome (PCOS) is one of the most common reproductive health problems of women, causing irregular periods and potential infertility amongst other challenging symptoms. Effective treatment remains a significant challenge and is largely achieved through hormonal medication and lifestyle changes. This third edition covers the aetiology, pathology, impact on fertility and effective medical and surgical management. The content has been thoroughly revised in line with updated guidelines and research developments in the field. A new chapter on the patient’s perspective has been included, bringing valuable insight into the lived experience of the condition. Mood disorders and the psychological aspects of PCOS are also covered for the first time. This is a key reference for all clinicians involved in the care of patients with PCOS, including gynaecologists, IVF specialists and reproductive endocrinologists.

• Thoroughly updated in line with new guidelines and recent research developments in the field, readers can be sure the advice given is up to date and effective.
• Authors are leading authorities in the field, providing key insights from years of experience caring for patients with PCOS.
• The inclusion of new chapters on a patient’s perspective and the psychological aspects of PCOS supports the growing recognition of the mental health impacts of the condition on women.

Contents
List of Contributors vi
1 Introduction to and History of Polycystic
Ovary Syndrome 1
Gabor T. Kovacs
2 Polycystic Ovary Syndrome: From
Phenotype to Genotype 8
Joop S. E. Laven and Yvonne
V. Louwers
3 The Epidemiology of Polycystic Ovary
Syndrome 21
Larisa Suturina
4 Ovarian Ultrasonography in Polycystic
Ovary Syndrome 29
Heidi Vanden Brink and Marla
E. Lujan
5 The Classification of Polycystic Ovary
Syndrome Informed by the International
Guideline 2018 45
Robert J. Norman, Rhonda Garad and
Helena Teede
6 The Relevance of the Anti-Müllerian
Hormone in Polycystic Ovary Syndrome
Diagnosis and Management 52
Martina Capuzzo and Antonio La
Marca
7 Origins of Polycystic Ovary Syndrome In
Utero 58
Roy Homburg and Claudia Raperport
8 Adrenal and Polycystic Ovary
Syndrome 67
Ozlem Celik and Bülent Okan Yildiz
9 Polycystic Ovary Syndrome and
Environmental Toxins 80
Eleni A. Kandaraki and Olga Papalou
10 Lifestyle in Polycystic Ovary
Syndrome 92
Rhonda Garad, Siew Lim and Lisa
Moran

11 Ovulation Induction in Polycystic Ovary
Syndrome 102
Evert J. P. van Santbrink
12 Ovarian Surgery for Ovulation
Induction 110
Gabor T. Kovacs
13 In Vitro Fertilization and Assisted
Reproductive Technologies in Polycystic
Ovary Syndrome 121
Susie Jacob and Adam Balen
14 Pregnancy Complications and Children
Outcomes in Patients with Polycystic
Ovary Syndrome 131
Femi Janse and Bart C. J. M. Fauser
15 The Role of In Vitro Maturation in
Polycystic Ovary Syndrome 142
Roger J. Hart and Melanie Walls
16 The Treatment of Obesity in Polycystic
Ovary Syndrome 150
Harry Frydenberg
17 Mood Disorders in Polycystic Ovary
Syndrome 162
Anuja Dokras
18 The Long-Term Health Consequences of
Polycystic Ovary Syndrome 170
Lisa Owens and Stephen Franks
19 Polycystic Ovary Syndrome: The Patient’s
Perspective 186
Sabra Lane
20 Cancer and Polycystic Ovary
Syndrome 189
Paul Hardiman
Index 201