Metabolomics in Food and Nutrition 1E

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Woodhead Publishing Series in Food Science, Technology and Nutrition

Introduction

Part I: Equipment, methods and data interpretation in metabolomics

Chapter 1: Equipment and metabolite identification (ID) strategies for mass-based metabolomic analysis

Abstract:

1.1 Introduction

1.2 Liquid chromatography

1.3 Gas chromatography

1.4 Mass spectrometry technologies

1.5 Analytical systems

1.6 Compound identification (ID) approaches

1.7 Databases for tracking and interconnections

1.8 Future trends

1.9 Sources of further information and advice

1.10 Acknowledgments

1.11 References

Chapter 2: Metabolomics using nuclear magnetic resonance (NMR)

Abstract:

2.1 Introduction

2.2 Experimental design and preparation

2.3 Experimental process and analysis

2.4 Current applications and future trends

2.5 References

2.6 Appendix: abbreviations

Chapter 3: Statistical methods in metabolomics

Abstract:

3.1 Introduction

3.2 Exploratory/visual approaches

3.3 Inferential approaches

3.4 Multiple hypothesis testing

3.5 Ensemble learning approaches

3.6 Conclusion

3.7 References

3.8 Appendix: software packages used

Chapter 4: Metabolic reconstruction databases and their application to metabolomics research

Abstract:

4.1 Introduction

4.2 Overview of Pathway/Genome Database (PGDB) construction

4.3 Querying PGDBs

4.4 Metabolomics applications

4.5 Sources of further information and advice

4.6 Conclusion

4.7 Acknowledgments

4.8 References

Part II: Applications of metabolomics in humans, plants and food

Chapter 5: Human samples for health assessments

Abstract:

5.1 Introduction

5.2 Sample collections and biobanks

5.3 Variation in metabolite profiles of human biofluids and tissues

5.4 Standards for metabolomic studies

5.5 Conclusions and future trends

5.6 References

Chapter 6: Metabolomics in nutrition

Abstract:

6.1 Introduction

6.2 Epidemiological studies and biomarkers of food intake

6.3 Diet and metabolic syndrome

6.4 The role of intestinal microbiota in nutrition

6.5 Perspectives in nutrition research

6.6 Future trends

6.7 References

Chapter 7: Current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications

Abstract:

7.1 Introduction

7.2 Analysis of human milk oligosaccharides (HMOs)

7.3 Applications of HMO analysis

7.4 Conclusion

7.5 References

Chapter 8: Metabolomic analysis of plants and crops

Abstract:

8.1 Introduction

8.2 Metabolomic studies on selected Poaceae species

8.3 Metabolomic studies on selected Solanaceae species

8.4 Metabolomic studies on selected Fabaceae species

8.5 Metabolomic studies on selected Brassicaceae and Lamiaceae species

8.6 Plant/crop metabolome databases

8.7 Future trends

8.8 References

Chapter 9: Metabolomics for the safety assessment of genetically modified (GM) crops

Abstract:

9.1 Introduction

9.2 Solanaceous crops

9.3 Cereal crops

9.4 Other crops

9.5 Metabolomics as part of a regulatory risk assessment procedure for the development and evaluation of genetically modified (GM) crops

9.6 Metabolomics and GM food safety: future trends

9.7 Acknowledgements

9.8 References

Chapter 10: Applications of metabolomics in food science: food composition and quality, sensory and nutritional attributes

Abstract:

10.1 Introduction

10.2 Metabolomics for compound identification: authentication and pathogen detection

10.3 Metabolomics for predicting sensory attributes

10.4 Metabolomics and food processing and safety

10.5 Conclusion

10.6 References