Metabolomics, Practical Guide to Design and Analysis
- ISBN: 9781498725262
- Εκδότης: Taylor & Francis
- Σελίδες: 290
- Έτος Έκδοσης: 2019
92,00€
Χωρίς ΦΠΑ: 86,79€
Metabolomics is the scientific study of the chemical processes in a living system, environment and nutrition. It is a relatively new omics science, but the potential applications are wide, including medicine, personalized medicine and intervention studies, food and nutrition, plants, agriculture and environmental science. The topics presented and discussed in this book are based on the European Molecular Biology Organization (EMBO) practical courses in metabolomics bioinformatics taught to those working in the field, from masters to postgraduate students, PhDs, postdoctoral and early PIs. The book covers the basics and fundamentals of data acquisition and analytical technologies, but the primary focus is data handling and data analysis. The mentioning and usage of a particular data analysis tool has been avoided; rather, the focus is on the concepts and principles of data processing and analysis. The material has been class-tested and includes lots of examples, computing and exercises.
Key Features:
Preface
Overview of Metabolomics - Oscar Yanes, Reza Salek, Igor Marin, Marta Cascante
Study Design and Preparation - Pietro Franceschi, Oscar Yanes and Ron Wehrens
Measurement Technologies - Oscar Yanes, Katherine Hollywood, Roland Mumm, Maria Vinaixa, Naomi Rankin, Ron Wehrens and Reza Salek
Mass Spectrometry Data Processing - Steffen Neumann, Oscar Yanes, Roland Mumm, Pietro Franceschi
Nuclear Magnetic Resonance Spectroscopy Data Processing - Maria Vinaixa, Naomi Rankin, Jeremy Everett and Reza Salek
Statistics: the essentials - Ron Wehrens and Pietro Franceschi
Data fusion in metabolomics - Johan A. Westerhuis, Frans van der Kloet, Age K. Smilde
Genome-scale metabolic networks - Clément Frainay & Fabien Jourdan
Metabolic flux - Igor Marín de Mas and Marta Cascante
Data Sharing and Standards
Conclusion
Appendix: Metabolic and transcriptional response of Arabidopsis thaliana wildtype and mutants to Phytophthora infestans - Tilo Lübken, Michaela Kopischke, Kathrin Geissler, Lore Westphal, Dierk Scheel, Steffen Neumann, Sabine Rosahl