Metastatic Diseases. Novel Approaches in Diagnosis and Therapeutic Management

This insightful volume opens new horizons for exploring modern therapeutic entities and emerging targets for combating the deadly disease of cancer. The authors provide a review of cancer along with descriptions of its molecular level mechanisms and emphasize the role of promising new therapies, including herbal therapies, that can be utilized for the treatment of metastatic diseases. The chapters look at specific approaches that have been researched and developed and that have almost reached the standardization stage, such as intracellular mechanisms, particularly phosphoprotein-enriched astrocytes and transthyretin proteins; CXCR4; autophagy-inhibiting drugs; spatiotemporal genetic analysis; tyrosine kinase inhibitors; and more. Also considered are advances in diagnostic systems like intra vital microscopy and molecular imaging.

CONTENTS

1. A Review on Cancer: From Clinical Perspective to Chemotherapy 2. Phosphoprotein-Enriched Astrocytes as Potential Anti-Cancer Agents 3. Autophagy-Inhibiting Drugs as Complements to Cancer Chemotherapy 4. Transthyretin Protein in Renowned Metastatic and Other Conditions 5. Role of CXCR4 Receptor Protein in Cancer Development and Therapies 6. C3D Complement System in Immunotherapy-Based Cancer Treatment 7. BH3 Mimetics 8. Spherical Nucleic Acid Platform-Based Drug Delivery for Brain Cancer and Improved Blood-Brain Barrier Crossing for Alzheimer’s and Other Diseases 9. Intra-Vital Microscopy: A New Amelioration in Cancer Immunotherapy Monitoring 10. Molecular Imaging: A New Advancement in Cancer Immunotherapy Monitoring 11. Spatiotemporal Genetic Analysis (SAGA) Technique for Cancer Cell Biology Studies 12. Plant-Derived Anti-Malarial Compounds and Their Derivatives as Anticancer Agents: Future Perspectives 13. Epigenetic Control of the Immune System and Its Applications in Metastatic Diseases 14. Immune Checkpoint Inhibitors 15. Tyrosine Kinase Inhibitors in Lymphocytic Leukemia 16. Cyclooxygenase-1 (COX-1) Inhibitors in the Management of Neoplastic Disorders 17. Microfluidic Devices in Capturing Circulating Metastatic Cancer Cell Clusters