Micro and Nanotechnology in Vaccine Development

Edited by Mariusz Skwarczynski, Vice-Chancellor and Fellow, University of Queensland, Australia and Istvan Toth, ARC Australian Professorial Fellow, Chair in Biological Chemistry, Professor of Pharmacy, Group Leader, IMB Division of Structural Biology   Features:

• Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development
• Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development
• Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines
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• Table of Contents

  Overview of immune system.
  Innate immunity and special role of antigen presenting cells.
  Immunity and size.
  Introduction to the vaccines.
  Current challenges in vaccine development.
  Growing role of nanotechnology
  Nanotechnology in medical research
  Nanoparticle based peptide vaccines
  Liposome as nano- and microvaccines
  Lipid in peptide vaccine (excluding liposomes)
  Nanoadjuvants for peptide based vaccines
  Nanopatches for vaccine delivery
  Oral vaccine delivery
  Nano- and microtechnology in skin delivery of vaccines
  Nasal vaccine delivery
  Nanoparticles for cancer targeting vaccines by
  polymer based nanovaccines
  Lipidic microparticles for vaccine delivery
  Polymeric microparticles for vaccine delivery

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  Description

  This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress.

  MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles.

  Key Features

  • Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development
  • Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development
  • Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines

  Readership

  Academic (researchers and grad students); Investigators in translational research; clinical scientists; pharmaceutical companies and development laboratories