Natural Products and Nano-Formulations in Cancer Chemoprevention

This book covers various aspects of cancer chemoprevention, including an overview of chemoprevention in the process of tumorigenesis; the roles of various phytochemicals, functional foods, and dietary interventions in disease prevention; and techniques such as cancer stem cell targeting, nano-formulations, and so forth.

The nutrigenomic and epigenetic effects of natural products at the molecular and genetic levels are also covered alongside their potential for additive and synergistic effect, as well as overcoming drug resistance. The key selling features of the book are as follows:

• Discusses holistic and comprehensive areas of chemoprevention
• Includes diverse techniques, such as cancer stem cell targeting, nano-formulations, and nanotechnology-based drug delivery systems
• Introduces various mechanisms involved in prevention of the diseases, including targeting cancer stem cells
• Reviews various aspects which can reduce the toxicity and cost of treatment of diseases by alternative medicine
• Explores various sources, mechanisms, and ways to develop cancer chemopreventive agents with minimal toxicity compared to traditional cancer therapy drugs

This book is focused on researchers and graduate students in drug delivery and formulation, nanobiotechnology, cancer chemoprevention, prevention, and therapeutics.

CONTENTS

1 Overview of Natural Products and Nano-Formulations in Cancer Chemoprevention

Ananya Bahuguna, Shiv Kumar Dubey, Kanchan Gairola, and Rohit Pujari

2 Polyphenols in Cancer Chemoprevention

Pushpendra Koli, Dinesh K. Yadav, Mahesh K. Samota, and Sandeep Kumar

3 Fat-Soluble Vitamins in Cancer Chemoprevention

Neetika Naudiyal, Gaurav Singh Rana, Ankur Adhikari, and Shiv Kumar Dubey

4 Targeting Cancer Stem Cells by Natural Products for Chemoprevention

Kamana Singh, Prabha Arya, and Ram Sunil Kumar L.

5 Functional Foods in Cancer Chemoprevention and Therapeutics

Shreya Joshi, Pranshu Sharma, and Atul Kumar Joshi

6 Phytochemicals: Potential Source of Interventions in Cancer Prevention and Treatment

Sonu Kumar Mahawer, Himani, Sushila Arya, Tanuja Kabdal, Ravendra Kumar, and Om Prakash

7 Nano-Formulation-Based Approaches for Chemoprevention

Dipanjana Ghosh, Wean Sin Cheow, and Rohit Saluja

8 Potential of Natural-Product-Based Nano-Formulations as Chemopreventive Agents

Sneh Gautam, Pushpa Lohani, Shiv Dutt Purohit, Sonu Ambawani, and Pooam Maan

9 Nano-Formulations of Chemotherapeutic Drugs: Recent Outlook, Advances, and Challenges in Cancer Management

Deepa Bisht, Shilpa Maddheshiya, Seema Nara, and Manisha Sachan

10 Nutrigenomics in Cancer Chemoprevention

Kanchan Gairola, Shiv Kumar Dubey, Ananya Bahuguna, and Shruti

11 Synergistic Effects of Natural Products in Cancer Treatment

Ritu Saini, Chitra Gupta, Shalini Pundir, Meenakshi Bajpai, Akansha Agrwal, and Sharad Visht

12 Medicinal Chemistry, Pharmacodynamics, and Pharmacokinetics of Camptothecin and Its Derivatives in Clinical Chemotherapeutics

Thadiyan Parambil Ijinu, Parameswaran Sasikumar, Vandhanam Aparna, Sreejith Pongillyathundiyil Sasidharan, Vipin Mohan Dan, Farkhodjon Tukhtaev, Varughese George, and Palpu Pushpangadan

13 Brassica Phytochemicals: A Potential Source of Cancer Prevention and Treatment

Himanshu Punetha and Shivanshu Garg

14 Opportunities with Nano-Formulations in Cancer Chemoprevention

Akansha Agrwal and Sheetal Mittal

15 Obstacles in Utilizing Nanomedicine for Cancer Management

Kamana Singh, Vineeta Kashyap, and Addanki P Kumar

16 Mangroves as an Alternative Source of Anticancer Drug Leads: Current Evidence and Future Prospects

Vasantha Kavunkal Hridya, Kokkuvayil Vasu Radhakrishnan, Nainarpandiyan Chandrasekar, and Thadiyan Parambil Ijinu