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Neurobiology of Disease 2nd Edition

Neurobiology of Disease 2nd Edition
Neurobiology of Disease 2nd Edition
  • Συγγραφείς: Johnston
  • ISBN: 9780199937837
  • Εκδότης: Oxford University Press
  • Σελίδες: 1434
  • Διαστάσεις: 279x216mm
  • Έτος Έκδοσης: 2016
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  • Includes nearly 200 brief, but substantial survey articles on all the major disorders of the nervous system in both adults and children;
  • Includes relevant diagnoses and treatment from the perspective of cutting edge clinical and basic neurobiological research;
  • Each chapter is illustrated with detailed figures, supplemented with descriptive and diagnostic tables, and thoroughly referenced for further investigations;
  • Written by clinicians who are experts in their fields and active participants in clinical and basic research.


    Description

    The second edition of Neurobiology of Disease includes nearly 200 articles surveying all major disorders of the nervous system in both adults and children, focusing on relevant diagnosis and treatments from the perspective of cutting edge clinical and basic neurobiological research.

    Akin to an encyclopedia of every neurologic disorder, this comprehensive work is ideal for graduate and medical school students, residents, and candidates preparing for their board certification examinations. Each chapter is illustrated with detailed figures, supplemented with descriptive and diagnostic tables, and thoroughly referenced for further investigations.

    The book's editors, Michael Johnston, Harold Adams, and Ali Fatemi bring their unique expertise in clinical and research neurology to the overall scope of this work. To further enhance the scope and quality of this new edition, the following Section Editors provided oversight of their respective sections:

    · Movement Disorders- Joel Perlmutter, Washington University
    · Dementias- David Knopman, Mayo Clinic
    · Motorneuron Diseases- Merit Cudkowicz, Massachusetts General Hospital
    · Paroxysmal Disorders- Solomon Moshe, Albert Einstein College of Medicine
    · Pediatric Neurology and Developmental Disorders- Tanjala Gipson and Deepa Menon, Kennedy Krieger Institute and Johns Hopkins University
    · Neuroimmunological Diseases- Carlos Pardo-Villamizar, Johns Hopkins University
    · Cerebrovascular Diseases- Harold Adams, University of Iowa
    · Peripheral and Autonomic Nervous System Disorders and Pain- Nicholas Maragakis, Johns Hopkins University
    · Neoplastic and Paraneoplastic Diseases- Lisa DeAngelis, Memorial Slaon-Kettering Cancer Center

    Table of Contents

    SECTION I: Movement Disorders (Joel Perlmutter, Washington University)
    1. History of Parkinsonism
    Michael Silver, MD and Stewart A. Factor, DO
    2. Parkinson Disease: Pathophysiology, Clinical Manifestations and Course including Diagnosis and Differential Diagnosis
    Michael J. Soileau, MD and Kelvin L. Chou, MD
    3. Parkinson Disease: Treatment, Current Clinical Trials
    Thien Thien Lim, MD and Hubert H. Fernandez, MD
    4. Parkinson Syndromes: Multiple System Atrophy
    Melvin W. Kong, MD and Ejaz A. Shamim MD, MS
    5. Parkinson Syndromes: Progressive Supranuclear Palsy
    Vikas Kotagal, MD, MS and Praveen Dayalu, MD
    6. Parkinson Syndromes: Corticobasal Degeneration
    Sami Barmada, MD, PhD
    7. Huntington Disease: Etiology, Genetics, and Clinical Manifestations
    Roger L. Albin, MD and Henry L. Paulson, MD, PhD
    8. Huntington Disease: Treatment, Current Clinical Trials
    Charles S. Venuto, PharmD and Karl Kieburtz, MD, MPH
    9. Essential Tremors
    Arif Dalvi, MD, MBA, Kelly E. Lyons, PhD, and Rajesh Pahwa, MD
    10. Dystonia: History and Classification
    H. A. Jinnah, MD, Cecilia N. Prudente, MD, Samuel J. Rose, MD and Ellen J. Hess, MD
    11. Dystonia: Pathophysiology, Clinical Manifestations and Course Including Diagnosis, and Differential Diagnosis, Treatment, Current Clinical Trials
    Jeri Yvonne Williams, MD and David G. Standaert, MD, PhD
    12. Paroxysmal Dyskinesias
    Olga Waln, MD and Joseph Jankovic, MD.
    13. The Expanded Polyglutamine Tract Spinocerebellar Ataxias
    Elsdon Storey, MD
    14. Ataxias: Autosomal Recessive and other Ataxias
    Vikram G. Shakkottai, MD, PhD
    SECTION II: Dementias (David Knopman, Mayo Clinic)
    15. Alzheimer's Disease: Pathology and Pathogenesis
    Bradley T Hyman, MD, Beatriz G Perez-Nievas, MD, Isabel Barroeta-Espar, MD, Alberto Serrano-Pozo, MD, Matthew Frosch, MD, and Teresa Gomez-Isla, MD
    16. Alzheimer's Disease: Clinical Manifestations and Diagnostic/Differential Diagnosis
    Michael S. Rafii, MD, PhD
    17. Alzheimer's Disease: Management and Treatment
    Gregory A. Jicha, MD, PhD and Frederick A. Schmitt, PhD
    18. Frontotemporal Degenerations
    Jonathan Graff-Radford, MD, and Keith A. Josephs, MD, MST, MSc
    19. Diagnosis and Therapy for Lewy Body Dementia
    Bela R. Turk, MD and Ali Fatemi, MD
    20. Pathogenesis of Lewy Body Dementia
    Jagan A. Pillai, MD, PhD and James B. Leverenz, MD
    21. Cerebrovascular Dementia
    Rahul Karamchandani, MD and Nancy R. Barbas, MD, MSW
    SECTION III: Motorneuron Diseases (Merit Cudkowicz, Massachusetts General Hospital, Harvard University)
    22. Types of MNDS
    Nimish Thakore, MD and Erik P. Pioro, MD, PhD
    23. Clinical Presentations, Diagnostic Criteria, Lab Testing
    Nimish Thakore, MD and Erik P. Pioro, MD, PhD
    24. Symptomatic Care
    Matthew Gladman, MD and Lorne Zinman, MD, MSc
    25. ALS: Epidemiology
    Éilis J. O'Reilly, ScD
    26. ALS: Pathogenesis
    Laura Ferraiuolo, MD and Stephen J. Kolb, MD
    27. ALS: Insights from Genetics
    Matthew B. Harms, MD and Timothy M. Miller, MD, PhD
    28. ALS: In Vitro and In Vivo Disease Models
    Brian J. Wainger, MD, PhD
    29. ALS Pathology
    Brent T. Harris, MD, PhD, Galam A. Khan, MD, and Saed Sadeghi, MD
    30. ALS: Clinical Trials Past Reflections Informing New Directions
    Katharine A. Nicholson, MD and James D. Berry, MD
    31. Upper Motor Neuron Disorders: Hereditary Spastic Paraplegia and Primary Lateral Sclerosis
    John K. Fink, MD
    32. UMN Disorders (HSP and PLS): Pathogenesis, Insights from Genetics, In Vitro and In Vivo Disease Models, Pathology and Clinical Trials
    Sabrina Paganoni, MD, PhD and Nazem Atassi, MD, MMSc
    33. SMA: Pathogenesis
    Umrao R. Monani, PhD and Darryl C. De Vivo, MD
    34. SMA: Insights from Genetics
    Arthur H.M. Burghes, MD and Vicki L. McGovern, MD
    35. SMA: In Vitro and In Vivo Models of Spinal Muscular Atrophy
    W. David Arnold, MD and Arthur H.M. Burghes, MD
    SECTION IV: Paroxysmal Disorders (Solomon Moshe, Albert Einstein College of Medicine)
    36. Biological Basis of Primary Generalized Epilepsies-Genetics
    Carla Marini, MD and Renzo Guerrini, MD
    37. Biological Basis of Primary Generalized Epilepsies - Pathophysiology
    Mark W. Youngblood, MD and Hal Blumenfeld, MD
    38. Temporal Lobe Epilepsy
    Edward H. Bertram, MD
    39. Focal Cortical Dysplasias
    Ali Mahta, MD and Peter B. Crino, MD, PhD
    40. Biological Bases of Symptomatic Generalized Epilepsies in Children
    Dragos A. Nita, MD, Miguel A. Cortez, MD, Jose Luis Perez Velazquez, MD, and O. Carter Snead 3rd, MD
    41. Epilepsies that Occur Predominantly in Girls
    Lynette G Sadleir, MD, Jozef Gecz, MD, and Ingrid E Scheffer, MD
    42. Epidemiology of Epilepsy: Incidence, Prevalence, and Risk Factors
    Dale C Hesdorffer, PhD, MPH
    43. Clinical Presentation, Diagnosis, and Course- Epilepsy Syndromes with Focal Seizures
    Alex Boro, MD and Jerome Engel, Jr., MD
    44. Medical Management of Epilepsy
    Jules C. Beal, MD and Emilio Perucca, MD
    45. Neuroimaging in Epilepsy
    William A. Gomes, MD, PhD
    47. Alternative Therapies for Epilepsy: Dietary Treatments
    Carl E. Stafstrom, MD, PhD
    48. Migraine and Other Headache Disorders
    Robert W. Charlson, MD and Matthew S. Robbins, MD
    49. Neurobiology of Migraine
    Victor Rosenfeld, MD and John Stern, MD
    SECTION V: Pediatric Neurology and Developmental Disorders (Tanjala Gipson and Deepa Menon, Kennedy Krieger Institute and Johns Hopkins University)
    50. Autism and Intellectual Disabilities: Overview of Autism and Intellectual Disabilities
    Tanjala T. Gipson, MD and Michael V. Johnston, MD
    51. Tuberous Sclerosis Complex: Pediatric Aspects
    Tanjala T. Gipson, MD, Andrea Poretti, MD, Rebecca McClellan, MGC, CGC, and Michael V. Johnston, MD
    52. Neurofibromatosis Type 1
    David S. Wolf, MD, PhD
    53. Neurobiology of Autism and Intellectual Disability: Fragile X Syndrome
    Dejan B. Budimirovic, MD and Megha Subramanian, BA
    54. Autism and Intellectual Disabilities: PTEN Gene mutation
    Deepa U. Menon, MBBS, MD
    55. Rett Syndrome
    C.L. Smith-Hicks, MD and SakkuBai Naidu, MD
    56. Angelman Syndrome
    Kristin W. Barañano, MD, PhD
    57. Down Syndrome
    George T. Capone, MD
    58. Coffin-Lowry Syndrome
    Michael V. Johnston, MD
    59. Congenital Hypothyroidism
    Mary Lee Gregory, MD, PhD
    60. Pediatric Neurotransmitter Disorders
    Phillip L. Pearl, MD and William P. Welch, MD
    61. Attention Deficit-Hyperactivity Disorder
    Mihee J. Bay, MD and Bruce K. Shapiro, MD
    62. Diseases of Mitochondrial Energy Metabolism
    Jacqueline Weissman, MD, MS and Lisa Emrick, MD
    63. Genetic Metabolic Disorders: MethylmalonicAciduria
    Siddharth Srivastava, MD and Jeffrey Chinsky, MD PhD
    64. The Urea Cycle Disorders
    Andrea L. Gropman, MD, Belen Pappa, MD, and Nicholas Ah Mew, MD
    65. Phenylketonuria
    Hilary Vernon, MD, PhD
    66. Cerebral Creatine Deficiency Disorders
    Peter W. Schutz, MD and Sylvia Stockler, MD
    67. Congenial Disorders of Glycosylation
    Marc C. Patterson, MD, FRACP
    68. Glutaric Aciduria Type I
    Hilary Vernon, MD, PhD
    69. Lysosomal Storage Disroders
    Gustavo H.B. Maegawa, MD, PhD, FACMG
    70. Peroxisomal Disorders
    Gerald V. Raymond, MD, Mohamed Y. Jefri, MD, Kristin W. Baranano, MD, and Ali Fatemi, MD
    71. Leukodystrophies
    Ulrike Schrifl, MD, SakkuBai Naidu, MD, and Ali Fatemi, MD
    72. Cerebral Palsy
    Joan M. Jasien, MD, Bruce K. Shapiro, MD and Alexander H. Hoon, Jr., MD
    73. Neonatal Brain Injuries
    Katharina Goeral, MD, Ali Fatemi, MD, and Michael V. Johnston, MD
    74. The Neurobiology of Encephalopathy of Prematurity
    Gwendolyn J. Gerner, MD and Vera Joanna Burton, MD
    75. Epilepsy Syndromes in Childhood
    Verena Staedtke, MD and Eric H. Kossoff, MD
    76. Migraine and Headaches in Children
    Jessica Klein, MD and Christopher Oakley, MD
    77. Congenital Hydrocephalus
    Vera Joanna Burton, MD and Edward Ahn, MD
    78. Spina Bifida and Related Conditions
    Stephen L. Kinsman, MD
    79. Smith-Lemli-Opitz Syndrome
    Ryan W. Lee, MD
    80. Sickle Cell Anemia
    Eboni I. Lance, MD
    SECTION VI: Neuroimmunological Diseases (Carlos Pardo-Villamizar, Johns Hopkins University)
    81. The Epidemiology of Multiple Sclerosis: An Historical Perspective
    Kassandra L. Munger, ScD
    82. Multiple Sclerosis: Pathology
    Bogdan Florin Gh. Popescu, MD, Yong Guo, MD, and Claudia Francesca Lucchinetti, MD
    83. Multiple Sclerosis: MRI and Other Imaging Approaches in MS
    Martina Absinta, MD and Daniel S. Reich, MD, PhD
    84. Multiple Sclerosis: White Matter vs Grey Matter Involvment (The Cause of Disability in MS)
    Massimo Filippi, MD, and Maria A. Rocca, MD.
    85. Multiple Sclerosis: Monitoring disease activity and progression
    Pavan Bhargava, MD and Shiv Saidha, MBBCh, MD, MRCPI
    86. Symptomatic Treatment of Multiple Sclerosis
    Kathleen Costello, RN, BSN, MS
    87. Exercise and Multiple Sclerosis
    Jeffrey R Hebert, PT, PhD
    88. Multiple Sclerosis: Disease Modifying Therapies
    Pavan Bhargava, MD and Peter A. Calabresi, MD
    89. Neuromyelitis Optica
    Teri L. Schreiner, MD, MPH and Jeffrey L. Bennett, MD, PhD
    90. Acute Disseminated Encephalomyelitis
    Benjamin M. Greenberg, MD, MHS and Allen Desena, MD
    93. Paraneoplastic Neurological Disorders
    John C. Probasco, MD
    94. Anti-N-Methyl-D-Aspartate Receptor (NMDAR) Encephalitis
    Elizabeth M. Wells, MD, MHS
    95. Other Proven and Putative Autoimmune Disorders of the CNS: Anti-GAD Associated Neurological Disorders; Stiff-Person syndrome, Cerebellar Ataxia, Progressive Encephalopathy with Rigidity and Myoclonus (PERM), and Encephalitis.
    Scott D. Newsome, DO
    96. Other Proven and Putative Autoimmune Disorders of the CNS: Hashimoto's Encephalopathy
    Eoin P. Flanagan, MBBCh and Richard J. Caselli, MD
    97. Other Proven and Putative Autoimmune Disorders of the CNS: Neuro-Bechet's Syndrome
    Afshin Borhani Haghighi M.D and Bernadette Kalman, MD, PhD, DSc
    98. Post-Streptococcal Movement Disorders
    Davide Martino, MD and Gavin Giovannoni, MD
    99. Rasmussen Encephalitis
    Jan Bauer, MD and Christian G. Bien, MD
    100. Autoimmune Encephalitis
    Andrew McKeon, MD
    101. Other Proven and Putative Autoimmune Disorders of the PNS: Myasthenia gravis
    Doris G. Leung, MD
    102. Vasculitis of the central nervous system
    Christian Pagnoux, MD and Richard H. Swartz, MD
    SECTION VII: Cerebrovascular Diseases (Harold Adams, University of Iowa)
    103. Stroke Epidemiology and Impact: Mortality, Incidence, Prevalence, Stroke Subtypes, Sex, Race/Ethnicity, Geography U.S. and World
    Virginia J Howard, PhD
    104. Acute Ischemic Stroke
    Harold P. Adams, Jr., MD
    105. Neuroimaging of Acute Stroke
    Chelsea S. Kidwell, MD and Kambiz Nael, MD
    106. Common Risk Factors and Medical Prevention Therapies
    George Khouri, MD, Shelly Ozark, MD, and Bruce Ovbiagele, MD, MSc, MAS
    107. Surgical and Radiologic Intervention for Prevention of Ischemic Stroke
    Andrew Ringer, MD
    108. Unusual Causes of Stroke
    Enrique C. Leira, MD, MS
    109. Pediatric Stroke
    Melissa Chung, MD and Warren Lo, MD
    110. Vascular Biology of Cerebral Ischemia
    Jason A. Ellis, MD and E. Sander Connolly, Jr., MD
    111. Intracerebral Hemorrhage
    Craig Anderson, MD
    112. Subarachnoid Hemorrhage
    David Hasan, MD
    113. Genetics of Cerebral Ischemia including Genetic Syndromes
    Andrea Porretti, MD and Michael V. Johnston, MD
    114. Molecular Targets of Cerebral Ischemia
    Ryan J. Felling, MD, PhD
    115. Sturge-Weber Syndrome and related Cerebrovascular Malformation Syndromes.
    Angela Quain, MS and Anne M. Comi, MD
    SECTION VIII: Peripheral and Autonomic Nervous System Disorders and Pain (Nicholas Maragakis, Johns Hopkins University)
    116. Neuropathies Associated with Infection or Toxic Exposure
    Doris Leung, MD
    117. Mechanisms Contributing to the Development and Progression of Diabetic Polyneuropathy
    Lucy M. Hinder, PhD, Kelli A. Sullivan, PhD, Stacey A. Sakowski, PhD, and Eva L. Feldman, MD, PhD
    118. Diabetic and PreDiabetic Neuropathy
    Lindsay Zilliox, MD and James W. Russell, MD, MS, FRCP
    119. Anatomy, Localization, and Pattern Recognition of Peripheral Neuropathy
    Noah Kolb, MD and A. Gordon Smith, MD
    120. Drug Discovery of Neuropathic Pain
    Brian J. Wainger, MD, PhD
    121. Neuropathies, Autonomic
    Phillip A. Low, MD
    122. Animal Models of Peripheral Neuropathy and Neuropathic Pain
    Katelyn Donaldson, MD and Ahmet Höke, MD, PhD
    123. Diagnostic Tests and Clinical Scales for Peripheral Neuropathy
    John D. Markman, MD
    124. Complex Regional Pain Syndrome
    Frank S. Pidcock, MD
    125. Entrapment Neuropathies
    James W. Teener, MD
    126. Demyelinating Neuropathies
    John A. Goodfellow, MD, Amy I. Davidson, MD, and Hugh J. Willison, MD
    127. Immune Mediated Neuropathies
    John A. Goodfellow, MD, Amy I. Davidson, MD, and Hugh J. Willison, MD
    128. Radiculopathy and Plexopathy
    Michael Wheaton, MD, Dustin Nowacek, MD, and Zachary London, MD
    SECTION IX: Neoplastic and Paraneoplastic Diseases (Lisa DeAngelis, Memorial Slaon-Kettering Cancer Center)
    129. Infiltrative Astrocytomas: WHO grade II - Diffuse Astrocytoma; WHO grade III - Anaplastic Astrocytoma
    Aaron Mammoser, MD, MS
    130. Glioblastomas
    Aaron Mammoser, MD, MS
    131. Oligodendrogliomas
    Thomas J. Kaley, MD
    132. Primary CNS Tumores: Ependymomas
    Brett J. Theeler, MD and Mark R. Gilbert, MD
    133. Meningiomas
    Jennie Taylor, MD and Patrick Y. Wen, MD
    134. Pineal Region Neoplasms
    Neil Haranhalli, MD and Jerome J. Graber, MD, MPH
    135. Pituitary Tumors
    Toral R. Patel, MD and Viviane S. Tabar, MD
    136. Primary Central Nervous System Lymphoma
    Lisa M. DeAngelis, MD
    137. Familial CNS Tumor Syndromes: Neurofibromatosis Type 1
    Ibrahim Hussain, BA and David H. Gutmann, MD, PhD
    138. Familial CNS Tumor Syndromes: Neurofibromatosis Type-2
    Jennie W. Taylor, MD and Scott R. Plotkin, MD, PhD
    139. Familial CNS Tumor Syndromes: Tuberous Sclerosis
    Darcy A. Krueger, MD, PhD
    140. Familial CNS Tumor Syndromes: Von Hippel-Lindau Disease
    Gurvinder Kaur, MD, Leonel Ampie, MD, Joseph Weiner, MD, and Aruna Ganju, MD
    141. Pediatric Tumors: Pontine Glioma
    Kristin Schroeder, MD, MPH and Oren Becher, MD
    142. Pediatric Tumors: Medulloblastoma
    Kevin C De Braganca, MD and Roger J. Packer, MD
    143. Pediatric Tumors: Cerebellar Astrocytoma
    Vijay Ramaswamy, MD, FRCPC, Jason T. Huse, MD, PhD, and Yasmin Khakoo, MD
    144. Brain Metastases
    Jasmin Jo, MD and David Schiff, MD
    145. Overview: Other Proven and Putative Autoimmune Disorders of the CNS
    Myrna R. Rosenfeld, MD, PhD, Maarten J. Titulaer, MD, PhD, and Josep Dalmau, MD, PhD
    146. Chemotherapy and Radiation Therapy
    Mary R. Welch, MD and Craig Nolan, MD
    SECTION X: Infectious Diseases of the Nervous System (Karen Roos, Indiana University)
    147. Acute Bacterial Meningitis
    Pratibha Singhi, MD, PhD, Naveen Sankhyan, MD, PhD, and Sunit Singhi, MD, PhD
    148. Cerebrospinal Fluid
    John E. Greenlee, MD
    149. History of Human Immunodeficiency Virus Infection and the Nervous System
    Avindra Nath, MD
    150. HIV-Associated Neurocognitive Disorders
    Joshua Alexander, DO, MPH, David J Croteau, MD, FRCPC, and Ronald J Ellis, MD, PhD
    151. HIV Infection: Opportunistic Infections in HIV-Infected Individuals
    William Tyor, MD
    152. Varicella Zoster Virus Infection of the Nervous System
    Don Gilden, MD, Randall J. Cohrs, PhD, Ravi Mahalingam, PhD, and Maria A. Nagel, MD
    153. Brain Abcess
    Bela R. Turk, MD, Ali Fatemi, MD, and Michael V. Johnston, MD
    154. Epidural Abscess and Sudural Empyema
    Tyler R West, DO and Kelly J Baldwin, MD
    155. Spinal Epidural Abcess
    Minal A. Shah, MD and Rabih O. Darouiche, MD
    156. Transverse Myelitis
    Ivana Vodopivec, MD, PhD and Tracey A. Cho, MD
    157. CNS Tuberculosis
    Andrea T. Cruz, MD, MPH, and Jeffrey R. Starke, MD
    158. Rabies
    Alan C. Jackson, MD
    159. Disorders Caused by Botulinum Toxin and Tetanus Toxin
    Carl E. Stafstrom, MD, PhD
    160. Rickettsial Diseases
    Lisa Sun, MD and Michael V. Johnston, MD
    161. Ehrlichial Diseases
    Nicholas S. Havens, MD and William E. Roland, MD, FACP
    162. Nervous System Lyme Disease
    John J. Halperin, MD
    163. Congenital and Perinatal Viral Infections
    James F. Bale, Jr., MD
    164. Neurologic Manifestations of HTLV-1
    Abelardo Q-C Araujo, MD, MSc, PhD, FAAN
    165. Fungal Infections of the Central Nervous System
    Pratibha Singhi,MD, Karthi Nallasamy, MD, and Sunit Singhi, MD
    166. Malaria
    Kiran Thakur, MD
    167. Babesiosis
    Kristyn E. Feldman, MD and Joshua Biddle, MD
    168. Amebic Encephalitis
    Pratibha Singhi, MD and Arushi G. Saini, MD
    169. Prions
    James A. Mastrianni, MD, PhD and Joshuae G. Gallardo, MD
    170. Neurological Complications of Infective Endocarditis
    Jonah Grossman, MD, Tanzila Shams, MD, and Cathy Sila, MD
    171. Post-Infectious Encephalitis
    Agusto A. Miravalle, MD
    172. Central Nervous System Whipple Disease
    Arun Venkatesan, MD, PhD
    173. Progressive Multifocal Leukoencephalopathy
    Arun Swaminathan, MBBS and Joseph R. Berger, MD
    SECTION XI: Sleep Disturbances (Mark Dyken, University of Iowa)
    174. REM Sleep Behavior Disorder
    Shannon S. Sullivan, MD
    175. Restless Leg Syndrome and Periodic Limb Movements in Sleep
    Jennifer Accardo, MD, MSCE
    176. Insomnia
    Wilfred R. Pigeon, MD and Henry J. Orff, MD
    177. Sleep Apnea
    Jennifer Accardo, MD, MSCE
    178. Neurobiology of Circadian Rhythm Disorders
    Christopher R. Jones, MD, PhD
    SECTION XII: Substance Abuse and Toxicological Disorders (Barry Kosofsky, Weil-Cornell University Medical Centers)
    179. Neurologic Manifestations of Organic Chemicals
    John L. O'Donoghue, VMD, PhD, DABT
    180. Neurobiology of Drug Addiction and Clinical Aspects of Drug Abuse
    Leslie R. Whitaker, MD and Bruce T. Hope, MD
    181. Neurological Effects of Marine Toxins
    Kazuma Nakagawa, MD
    182. Fetal Alcohol Syndrome
    Carmen Lopez-Arvizu, MD, Carmel Bogle, MD, and Harolyn M.E. Belcher, MD, MHS
    183. Fetal Exposure to Tobacco and Cannabis
    Edore C. Onigu-Otite, MD
    184. Neurobiology of Child Maltreatment and Psychological Trauma
    Nikeea Copeland-Linder, PhD, MPH, Edore Onigu-Otite, MD, Jennifer Serico, PhD, Mariflor Jamora, MD, and Harolyn M.E. Belcher, MD, MHS
    185. Neurobiology of Intrauterine Opiate and Cocaine Exposure
    Harolyn M.E. Belcher, MD, MHS and Samantha Hutchison, MD
    SECTION XIII: Neurologic Manifestations of Medical Disorders (John Probasco, Johns Hopkins University)
    186. Electrolyte Disturbances
    Mark N. Rubin, MD and Alejandro A. Rabinstein, MD
    187. Nutritional Deficiencies
    Deanna Saylor, MD, MHS and John C. Probasco, MD
    188. Alcohol Abuse
    Killian A. Welch, MD
    189. Thyroid Disease
    Makoto Ishii, MD, PhD
    190. Parathyroid, Adrenal, Ovarian, Testicular and Pituitary Disease
    Gary M. Abrams, MD
    191. Cardiac Disease
    Roger E. Kelley, MD
    192. Neurobiology of Brain Injury after Cardiac Arrest
    Lucia Rivera-Lara, MD and Romergryko G. Geocadin, MD
    193. Gastrointestinal Disease
    Brian P. Bosworth, MD, Brian R. Landzberg, MD, and Elisa McEachern, MD
    194. Neurological Manifestations of Renal Disease
    Joshua S. Hundert, MD, Rashmi Verma, MD, Ritika Suri, MD, Anika T. Singh, MD, and Ajay Singh, MD
    195. Systemic Lupus Erythematosis
    Richard B. Rosenbaum, MD
    196. Neurologic Manifestations of Hematological Disease
    Elham Bayat, MD

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