Toxicological Risk Assessment of Chemicals: A Practical Guide

Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk assessment of chemical substances. It illustrates each step in the process: hazard identification, a dose response assessment, and exposure assessment. It also summarizes basic concepts of interaction of chemicals in mixtures and discusses various approaches to testing such mixtures. Features: standards from all international regulatory agencies; the steps in risk assessment, including hazard identification, exposure assessment, and risk characterization; the assessment of multiple chemical exposures or chemical mixtures; data from both human and animal studies; and the linearized multi-stage mathematical model widely used by the US EPA for characterizing.