Nutritional And Therapeutic Interventions For Diabetes and Metabolic Syndrome

Diabetes mellitus affects approximately 20 million people in the US, or nearly 7% of the population. It is expected to increase by 70% within the next 25 years and numerous epidemiologic studies have demonstrated that type 2 diabetes increases the risk of cardiovascular morbidity and mortality. It is estimated to cost over $92 BILLION in health care costs and lost productivity. The increased risk is due to the detrimental vascular effects of prolonged exposure to a hyperglycemic, oxidant rich environment yielding associated cardiovascular risk factors: atherosclerosis, hypertension and clotting abnormalities. Hypertension and dyslipidemia in diabetic patients produces substantial decreases in cardiovascular and micro vascular diseases.

NUTRITIONAL AND THERAPEUTIC INTERVENTION OF DIABETES AND METABOLIC SYNDROME provides an overview of the current epidemic, outlines the consequences of this crisis and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. The contributing experts from around the world give this book relevant and up-to-date global approaches to the critical consequences of metabolic syndrome and make it an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes.

PREFACE
SECTION 1 EPIDEMIOLOGY AND OVERVIEW
Chapter 1: Type1 Diabetes Mellitus: An Overview / Saleh Adi, Andrea Gerard Gonzalez
Chapter 2: An Overview on Type 2 Diabetes / Jonathan Pinkney, Julie Tomlinson, Elizabeth Stenhouse
Chapter 3: Pathogenesis of Type 2 Diabetes- A Comprehensive Analysis / Jeff Unger
Chapter 4: Managing the Broad Spectrum of Type 2 Diabetes / Evelyne Fleury-Milfort
Chapter 5: Prediabetes: Prevalence, Pathophysiology and Recognition of Enhanced Risk / Alok K. Gupta, Ajay Menon, William D. Johnson
Chapter 6: Obesity and Type 2 Diabetes in Youths: New Challenges to Overcome / Santoro Nicola, Cosimo Giannini, Sonia Caprio
Chapter 7: Diabetes Pathophysiology- A Nutritional Perspective / Kevin J. Acheson
Chapter 8: Diabetes pathophysiology- A Nurse’s Perspective / Anne Jessup
Chapter 9: Roles of Environmental Pollution and Pesticides in the Metabolic Syndrome and Diabetes:  The Epidemiological Evidence / Ivar L. Frithsen, Charles J. Everett
Chapter 10: Preventing Diabetes with Diet and Exercise / Karen Z. Walker, Kerin O'Dea

SECTION 2 TYPES OF DIABETES AND ITS CORRELATION WITH OTHER DISEASES
Chapter 11: The Role of Insulin Resistance in the Cardiorenal Syndrome / Jaya P. Buddineni, Adam Whaley-Connell, James Sowers
Chapter 12: An Overview on Diabetic Nephropathy / Kei Fukami, Sho-ichi Yamagishi
Chapter 13: An Overview on Diabetes and Ocular Health / Shintaro Nakao, Yasuaki Hata
Chapter 14: An Overview on Diabetic Retinopathy / Stephen G. Schwartz, Harry W. Flynn, Jr.
Chapter 15: Role of Peripheral Neuropathy in the Development of Foot Ulceration and Impaired Wound Healing in Diabetes Mellitus / Francesco Tecilazich, Thanh L. Dinh, Aristidis Veves
Chapter 16: An Overview on Gestational Diabetes / Christopher Federico, Gabriella Pridjian

SECTION 3 MOLECULAR INSIGHTS OF DIABETES AND METABOLIC SYNDROME
Chapter 17: Gene-Environment Interaction in the Pathogenesis of Type 2 Diabetes / Kian-Peng Goh
Chapter 18: Epigenetics in the Pathophysiology of Type 2 Diabetes / Charlotte Ling
Chapter 19: Targeting the metabolic syndrome and Type 2 Diabetes by preventing inflammation / Amin Ardestani, Luan Shu, Kathrin Maedler
Chapter 20: Interleukin-18 in Metabolic Syndrome and Diabetes / Marius Trøseid, Harald Arnesen, Ingebjørg Seljeflot

SECTION 4 PATHOPHYSIOLOGY
Chapter 21: Sleep, Hypertension and Diabetes / Michelle A. Miller, Frances P. Cappuccio
Chapter 22: Roles of Pancreatic Cell Functions, Liver, Skeletal Muscle and Adipose Tissues in Diabetes and Metabolic Syndrome / Beverly S. Mühlhäusler
Chapter 23: Liver Disease: A Neglected Complication of Diabetes Mellitus / Marco Arrese, Juan Pablo Arab, Juan Pablo Arancibia, Roberto Candia, Arnoldo Riquelme, Francisco Barrera

SECTION 5 PREVENTION AND TREATMENT 1: DIET, EXERCISE, SUPPLEMENTS AND ALTERNATIVE MEDICINES
Chapter 24: Antioxidants, Healthy Diet and Diabetes / Dario Pitocco, Francesca Martini, Francesco Zaccardi, Giovanni Ghirlanda
Chapter 25: Molecular Mechanisms of Diabetes Prevention by Structurally Diverse Antioxidants / Lucyna A. Wozniak, Katarzyna Cypryk, Marzena Wojcik
Chapter 26: Cardioprotective Roles of Selenium in Diabetes / Belma Turan, Guy Vassort
Chapter 27: Exercise and Physical Activity in the Prevention of Diabetes and Metabolic Syndrome / Cheri L. Gostic, Dawn Blatt
Chapter 28: An Overview on Nutraceuticals and Herbal Supplements for Diabetes and Metabolic Syndrome / Wadie I. Najm
Chapter 29: Therapeutic Effect of Fucoxanthin on Metabolic Syndrome and Type 2 Diabetes / Kazuo Miyashita, Show Nishikawa, Masashi Hosokawa
Chapter 30: Beneficial Effects of Chromium (III) and Vanadium Supplements in Diabetes / John B. Vincent
Chapter 31: Role of n-6 and n-3 Polyunsaturated Fatty Acids in Type 2 Diabetes / Jose Galgani, Pamela Rojas
Chapter 32: Effects of Supplemental Fiber in Type 2 Diabetes Mellitus / Candis M. Morello, Sarah A. Bajorek
Chapter 33: The Effects of Resveratrol on Diabetes and Obesity / Juan Sanchez, Mahesh Thirunavukkarasu, Nilanjana Maulik
Chapter 34: Meal Plans for Diabetics: Caloric Intake, Calorie Counting and Glycemic Index / Paulin Moszczynski, Jan Rutowski
Chapter 35: Ayurveda and Metabolic Diseases - Whole is greater than Sum of Parts / Amrutesh Puranik, Bhushan Patwardhan

SECTION 6 PREVENTION AND TREATMENT 2: DRUGS AND PHARMACEUTICALS
Chapter 36: The Evolution of Glucose-Lowering Drugs for Type 2 Diabetes / Andrew J. Krentz, Alan J. Sinclair
Chapter 37: Anti-Diabetic Drugs For Elderly Population / Raffaela Marfella, Giuseppe Paolisso

SECTION 7 DIABETES IN ANIMALS AND TREATMENT
Chapter 38: Diabetes Mellitus in Animals: Diagnosis and Treatment of Diabetes Mellitus in Dogs and Cats / Deborah S. Greco
Chapter 39: Overview of Diabetes Treatment in Animals / Erica L. Reineke

LIVING WITH DIABETES: A RUNNING COMMENTARY