Oxford Textbook of Clinical Nephrology Fourth Edition

 This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts.

The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field.

This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management.

Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence.

This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Onlineis mobile optimized for access when and where you need it.

VOLUME 1
Part 1: Assessment of the patient with renal disease
1: Aminu K. Bello, Marcello Tonelli, and Kitty J. Jager: Epidemiology of kidney disease
2: Chris Winearls: Clinical assessment of the patient with renal disease
3: Chris Winearls: Presentations of renal disease
4: Chris Winearls: Kidney disease focused history taking
5: Chris Winearls: Kidney disease focused features on examination
6: Walter P. Mutter: Urinalysis
7: Walter P. Mutter: Assessment of renal function
8: Walter P. Mutter: Tubular function
9: Michael Weston: Renal radiology: overview
10: Jeannette Kathrin and Peter Howells: Ionising radiation and radiation protection
11: Akira Kawashima and Andrew J. LeRoy: Plain radiography, excretion radiography, and contrast radiography
12: Steven Kennish: Intervention
13: Toby Wells and Simon Freeman: Ultrasound
14: Eugene Teoh and Michael Weston: Computed tomography
15: Kazuhiro Kitajima, Akira Kawashima. and James F Glockner: Magnetic Resonance Imaging
16: Ramya Dhandapani and Sobhan Vinjamuri: Radioisotopes in diagnostic imaging in nephrology
17: Jo H.M. Berden and Jack Wetzels: Immunological investigation of the patient with renal disease
18: Ian Roberts, Phil Mason and Agnes Fogo: The renal biopsy
19: Richard Haynes, Martin J Landry, William G Herrington, and Colin Baigent: Clinical trials- how and why in nephrology
Part 2: The patient with fluid, electrolyte, and renal tubular disorders
20: Matthew A. Bailey: An overview of tubular function
21: Laurent Schild: Sodium transport and balance: A key role for the distal nephron
22: David Marples and Soren Neilson: Water homeostasis
23: Alain Doucet and Gilles Crambert: Potassium homeostasis
24: Carsten Wagner and Olivier Devuyst: Renal acid-base homeostasis
25: Heini Murer, Juerg Biber, and Carsten Wagner: Phosphate homeostasis
26: Francesco Trepiccione and Gianni Capasso: Calcium homeostasis
27: Pascal Houillier: Magnesium homeostasis
28: Ewout Hoorn and Bob Zietse: Approach to the patient with hyponatraemia
29: Bob Zietse: Approach to the patient with hypernatraemia
30: Jean-Marie Krzesinski and Eric P. Cohen: Approach to the patient with oedema
31: Detlef Bockenhauer and Robert Kleta: Approach to the patient with salt-wasting
32: Daniel Bichet: Approach to the patient with polyuria
33: David Ellison and Arohan R. Subramanya: Clinical use of diuretics
34: Charles Wingo and I. David Weiner: Approach to the patient with hypo-/hyperkalaemia
35: Mitch Halperin and Kamel Kamel: Approach to the patient with metabolic acidosis or alkalosis
36: Stephen Walsh: Approach to the patient with renal tubular acidosis
37: Dennis Jose Joseph and Theresa A. Guise: Approach to the patient with hypercalcaemia
38: Agnes Linglart and Anne-Sophie Lambert: Approach to the patient with hypocalcaemia
39: Judith Blaine, Hector Giral-Arnal, Sabina Jelen, and Moshe Levi: Approach to the patient with hypo-/hyperphosphataemia
40: Martin Konrad and Karl Peter Schlingmann: Approach to the patient with hypomagnesaemia
41: Detlef Bockenhauer and Robert Kleta: Approach to the patient with renal Fanconi syndrome, glycosuria or aminoaciduria
Part 3: The patient with glomerular disease
42: Alexander Woywodt and Diana Chiu: The glomerulus and the concept of glomerulonephritis
43: Marlies Elger and Wilhelm Kriz: The renal glomerulus - the structural basis of ultrafiltration
44: Jean-Claude Dussaule, Martin Flamant, and Christos Chatziantoniou: Function of the normal glomerulus
45: Neil Turner: Mechanisms of glomerular injury: overview
46: John Neary and Neil Turner: The patient with haematuria
47: John Neary: Loin pain haematuria syndrome
48: John Neary and Neil Turner: Nutcracker syndrome and phenomenon
49: Neil Turner: Exercise-related pseudonephritis
50: Neil Turner and Stewart Cameron: Proteinuria
51: Neil Turner: Postural proteinuria (Benign orthostatic proteinuria)
52: Premil Rajakrishna, Stewart Cameron and Neil Turner: Nephrotic syndrome
53: Neil Turner and Premil Rajakrishna: Pathophysiology of oedema in nephrotic syndrome
54: Patrick Niaudet and Alain Meyrier: Idiopathic nephrotic syndrome: overview
55: Patrick Niaudet and Alain Meyrier: Minimal change disease: clinical features and diagnosis
56: Patrick Niaudet and Alain Meyrier: Minimal change disease: treatment and outcome
57: Patrick Niaudet and Alain Meyrier: Primary focal segmental glomerulosclerosis (FSGS): Clinical features and diagnosis
58: Patrick Niaudet and Alain Meyrier: Primary focal segmental glomerulosclerosis (FSGS): Treatment and outcome
59: Patrick Niaudet and Alain Meyrier: Pathogenesis of proteinuria in minimal change disease and FSGS
60: Daniel Cattran and Heather Reich: Membranous glomerulonephritis: overview
61: Daniel Cattran and Heather Reich: Membranous glomerulonephritis: clinical features and diagnosis
62: Daniel Cattran and Heather Reich: Membranous glomerulonephritis: treatment and outcome
63: Daniel Cattran and Heather Reich: Secondary membranous glomerulonephritis
64: Daniel Cattran and Heather Reich: Membranous glomerulonephritis: pathogenesis
65: Kar Nen Lai and Sydney C. W. Tang: Immunoglobulin A nephropathy: overview
66: Kar Nen Lai and Sydney C. W. Tang: Immunoglobulin A nephropathy: clinical features
67: Kar Nen Lai and Sydney C. W. Tang: Immunoglobulin A nephropathy: diagnosis
68: Kar Nen Lai and Sydney C. W. Tang: Immunoglobulin A nephropathy: treatment and outcome
69: Kar Nen Lai and Sydney C. W. Tang: Immunoglobulin A nephropathy: pathogenesis
70: Neil Turner: Crescentic (rapidly progressive) glomerulonephritis
71: Ciao Zhou, Neil Turner, and Ming-hui Zhao: Anti-glomerular basement membrane disease: overview
72: Ciao Zhou, Neil Turner, and Ming-hui Zhao: Anti-glomerular basement membrane disease: clinical features and diagnosis
73: Ciao Zhou, Neil Turner, and Ming-hui Zhao: Anti-glomerular basement membrane disease: treatment and outcome
74: Ciao Zhou, Neil Turner, and Ming-hui Zhao: Antiglomerular basement membrane disease: pathogenesis
75: Neil Turner: Alport post-transplant antiglomerular basement membrane disease
76: Bernardo Rodriguez-Iturbe and Mark Haas: Post-infectious glomerulonephritis: overview
77: Bernardo Rodriguez-Iturbe and Mark Haas: Post streptococcal glomerulonephritis
78: Bernardo Rodriguez-Iturbe and Mark Haas: Immunoglobulin A dominant post-infectious glomerulonephritis
79: Bernardo Rodriguez-Iturbe and Mark Haas: Glomerulonephritis associated with endocarditis, deep-seated infections and shunt nephritis
80: T. Cook and Daniel Gale: Membranoproliferative glomerulonephritis and C3 glomerulopathy
81: Stephen Korbet, Melvin M.Schwartz, and Edmund J. Lewis: Fibrillary and immunotactoid glomerulopathy
82: Alexander Woywodt and Diana Chiu: Drug induced and toxic glomerulopathies
Part 4: The patient with interstitial disease
83: Richard Baker and B.Chir: Acute tubulointerstitial nephritis: overview
84: Hassan Izzedine and Victor Gueutin: Drug-induced acute tubulointerstitial nephritis
85: Gregory L. Braden and Benjamin J. Freda: Other toxic acute tubulointerstitial nephritis
86: Adalbert Schiller, Adrian Covic, and Liviu Segall: Chronic tubulointerstitial nephritis: overview
87: Hassan Izzedine and Victor Gueutin: Drug-induced chronic tubulointerstitial nephritis
88: Patrick C D'Haese, Benjamin Vervaet, and A Verhulst: Heavy metals-induced tubulointerstitial nephritis
89: Refik Gökmen and Graham Lord: Aristolochic acid nephropathy caused by ingestion of herbal medicinal products
90: Milan Radovic and Adalbert Schiller: Balkan endemic nephropathy
91: Lisa Phipps and David C. Harris: Radiation nephropathy
92: D. H. Kang and M. Kanbay: Urate nephropathy
93: Liviu Segall and Adrian Covic: Immune-mediated tubulointerstitial nephritis
Part 5: The patient with reduced renal function
94: Ashish Upadhyay, Lesley Inker, and Andrew Levey: Chronic kidney disease: definition, classification, and approach to management
95: Morgan Grams and Josef Coresh: Chronic kidney disease in the developed world
96: LuXia Zhang and Haiyan Wang: Chronic kidney disease in developing countries
97: M. Beaulieu, C. Weber, N. Zalunardo and Adeera Levin: Chronic kidney disease long-term outcomes: progression, death, cardiovascular disease, infections, and hospitalizations
98: David Goldsmith: Cardiovascular disease and chronic kidney disease: overview
99: Charles Ferro and Khai Ping Ng: Recommendations for management of high renal risk chronic kidney disease
100: Teena Tandon and Rajiv Agarwal: Hypertension as a cause of chronic kidney disease: what is the evidence?
101: Juan Jesus Carrero, Xu Hong, and Bengt Lindholm: Diet and the progression of chronic kidney disease
102: Alan Jardine and Rajan Patel: Lipid disorders of patients with chronic kidney disease
103: Stephan R. Orth: Smoking in chronic kidney disease
104: Edmund Lamb and Finlay MacKenzie: Analytical aspects of measurements and laboratory values in chronic and acute kidney disease
105: Andrew Williams, Robert Fassett, Erin Howden, and Jeff Coombes: Effect of lifestyle modifications on patients with chronic kidney disease
106: Naveet Kumar, Peter McCulloch, Heather Henderson, and Beverly D. Cameron: Malnutrition, obesity, and undernutrition in chronic kidney disease
107: Carmine Zoccali, Francesca Mallamaci, and Davide Bolignano: Left ventricular hypertrophy in chronic kidney disease
108: Reza Hajhosseini, Kaivan Korvath, and David Goldsmith: Sudden cardiac death in chronic kidney disease
109: Patrick Biggar, Hansjoerg Rothe, and Markus Ketteler: Epidemiology of calcium, phosphate and PTH disturbances in chronic kidney disease
110: Juan Jesus Carrero and Peter Stenvinkel: The role of inflammation in chronic kidney disease
111: John Townend and Charles Ferro: Vascular stiffness in chronic disease - pathophysiology and implications
112: Nostratoli Vaziri: Oxidative stress and its implications in chronic disease
113: Thimoteus Speer and Danilo Fliser: Abnormal endothelial vasomotor and secretory function
114: Neeraj Dhaun and David Webb: Endothelins and their antagonists in chronic kidney disease
115: Stuart Sprague and Menaka Sarav: Chronic kidney disease-mineral and bone disorder: overview
116: Paulo Raggi and Luis D'Marco Gascon: Imaging for detection of vascular disease in chronic kidney disease patients
117: Alexandra Voinescu, Nadia Iqbal and Kevin Martin: Pathophysiology of chronic kidney disease - mineral and bone disorder
118: Alexandra Voinescu, Kevin Martin, Nadia Iqbal, and David Goldsmith: Management of chronic kidney disease - mineral and bone disorder
119: Orlando Gutierrez: Fibroblast growth factor 23, klotho, and phosphorus metabolism in chronic kidney disease
120: Adrian Covic, Mugurel Apetrii, Luminita Voroneanu, and David Goldsmith: Vascular calcification
121: Alastair Hutchison and Michael L. Picton: Fractures in patients with chronic kidney disease
122: Stuart Sprague and James Pullman: Spectrum of bone pathologies in chronic kidney disease
123: Iain Macdougall: Clinical aspects and overview of renal anaemia
124: Iain Macdougall and Jolanta Malyszko: Erythropoiesis-stimulating agents in chronic kidney disease
125: Jolanta Malyszko and Iain Macdougall: Iron metabolism in chronic kidney disease
126: Iain Macdougall: Iron management in renal anaemia
127: Kaivan Khavandi, Halima Amer, Sarah Withers, and Behdad Afzali: Pleoitropic effects of Vitamin D
128: Behdad Afzali and Claudia Kemper: Immunity
129: Fabrizio Fabrizi and Michel Jadoul: The liver and chronic kidney disease
130: Rishi Goel, Kamal Patel, and Terry Wong: Gastroenterology and renal medicine
131: Timur A. Galperin, Kieron S. Leslie, and Antonia J. Cronin: Cutaneous manifestations of end-stage renal disease (ESRD)
132: Tomas Agustsson and Paul Carroll: The patient with reduced renal function: endocrinology