About this book

The aim of this book is to provide concise information and quick reference on the basics and practice of PET/CT for beginners. The chapters are written by Nuclear Medicine experts from different countries with enormous experience in PET/CT practice.

Starting with the basics of PET/CT describing physics and the use of radiopharmaceuticals in PET/CT, the book explores the principle of PET/CT in radiotherapy planning. The last five chapters explore normal variation, pitfalls and artefacts commonly seen with various routinely used PET radiotracers. The text is enriched by tables and highlighted clinical cases for better understanding.

This book will be of interest mostly to nuclear medicine physicians and radiologists, but it may be appealing also to a wider medical community including oncologists and radiotherapists.

Table of contents (10 chapters)

Basic Principles of PET/CT Imaging

    Deborah Carrick, John Dickson, Andy Bradley

Pages 1-12
Physics of PET and Respiratory Gating

    April-Louise Smith, Richard Manber

Pages 13-20
The Physics of PET/CT for Radiotherapy Planning

    Matt Aldridge

Pages 21-25
18F-FDG and Non-FDG PET Radiopharmaceuticals

    James Ballinger, Gopinath Gnanasegaran

Pages 27-31
PET/CT Imaging: Patient Instructions and Preparation

    Shaunak Navalkissoor, Thomas Wagner, Gopinath Gnanasegaran, Teresa Szyszko, Jamshed B. Bomanji

Pages 33-38
18F-FDG PET/CT Imaging: Normal Variants, Pitfalls and Artefacts

    Kanhaiyalal Agrawal, Gopinath Gnanasegaran, Evangelia Skoura, Alexis Corrigan, Teresa Szyszko

Pages 39-62
68Ga-DOTA-Peptides PET/CT: Physiological Biodistribution, Variants and Pitfalls

    Ashik Amlani, Keerthini Muthuswamy, Kanhaiyalal Agrawal, Shaunak Navalkissoor, Gopinath Gnanasegaran

Pages 63-80
18F-methylcholine (FCH) PET/CT Imaging: Physiological Distribution, Pitfalls and Imaging Pearls

    Arun Kumar Reddy Gorla, Kanhaiyalal Agrawal, Ashwin Singh Parihar, Bhagwant Rai Mittal

Pages 81-91
68Ga-PSMA PET/CT: Normal Variants, Pitfalls and Artefacts

    Kanhaiyalal Agrawal, Sharjeel Usmani, Abdulredha Esmail, Fahad Marafi, Gopinath Gnanasegaran

Pages 93-107
18F-NaF PET/CT Imaging

    Sharjeel Usmani, Kanhaiyalal Agrawal, Abdulredha Esmail, Fahad Marafi, Gopinath Gnanasegaran

Pages 109-124

About the editors

Dr. Agrawal is a Nuclear Medicine physician working as Associate Professor in the Department of Nuclear Medicine at All India Institute of Medical Sciences, Bhubaneswar. He has completed his MD degree in Nuclear Medicine from the prestigious Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India and was awarded Kataria memorial Gold medal as best post graduate student of 2012. He was further trained as specialist registrar in the Guy’s and St. Thomas’ NHS Hospital Trust, London, UK. He authored and co-authored more than 50 scientific articles in reputed peer reviewed journals. He won several awards for scientific research paper. He is editor of the Indian Journal of Nuclear Medicine. His area of interest is hybrid molecular imaging in benign diseases, PET/CT and radionuclide therapy.

Annah Skillen graduated from the Charles Sturt University, Australia with a B Med Rad Sc (Nuc Med) in 2006 and subsequently worked at the John Hunter Hospital in Newcastle, Australia. In 2011 she relocated to the UK. She completed a M Med Rad Sc (Nuc Med) in 2012, and was awarded a JNMT editors’ choice award for the publication of her research on brown adipose tissue on 18F-FDG PET/CT. After various locum positions in London, she joined the Royal Free London NHS trust in 2013 to establish the PET/CT service. She relocated back to Australia in 2017 and is currently the Nuclear Medicine modality manager at South Coast Radiology, QLD. In 2019, she implemented the first fully digital PET/CT service within a private hospital in Australia.

Dr. Esmail achieved his Bachelor degree of Medicine, Surgery and Obstetric from National University of Ireland, University College Cork in 2001. By 2007 he completed his training program in nuclear medicine, a program offered by Kuwait Institute for Medical Specialization (KIMS), State of Kuwait. In 2008 he also obtained M.Sc. in Nuclear Medicine sciences from College of Higher Education, Faculty of Medicine, Kuwait University. In 2008 he received a fellowship training program in PET/CT Oncology, Cardiac Rb-82 PET/CT, Cardiac SPECT/CT (Division of Nuclear Medicine and Molecular Imaging at Emory University Hospital in Atlanta, GA, USA. Currently he is consultant at Jaber Al-ahmed Center for Nuclear Medicine and Molecular Imaging (JACNMMI), a center founded by Kuwait Foundation for Advancement of Sciences.

Dr. Usmani is a specialist in Nuclear Medicine at the Kuwait Cancer Control Center and member of the teaching staff at the Kuwait Institute of Medical Specialization. He has been awarded the Outstanding Doctor Award in KCCC for 2016 and most hardworking house officer: 2002 - Dept. of Medicine, Civil Hospital Karachi, Pakistan. His main research interest is in bone imaging with ¹⁸F-NaF PET/CT in non-oncological indications and ⁶⁸ Ga-PSMA Imaging in Prostate Cancer. He published 83 original articles, 3 books and 2 book chapters.