Pharmaceutical Dosage Forms: Parenteral Medications, Third Edition: Volume 1: Formulation and Packaging

Volume one provides:

• An historical perspective of injectable drug therapy, common routes of administration, and biopharmaceutics of NCEs and NBEs.
• An in-depth discussion on the preformulation and formulation of small and large molecules, including ophthalmic dosage forms.
• A presentation of parenteral primary packaging options - glass and plastic containers, as well as elastomeric closures.
• A definitive chapter on container-closure integrity.
• New chapters on solubility and solubilization, formulation of depot delivery systems and biophysical/biochemical characterization of proteins.

• 1. Parenteral Dosage Forms: Introduction and Historical Perspectives John D. Ludwig
• 2. Parenteral Drug Administration: Routes of Administration and Devices - Himanshu Bhattacharjee and Laura A. Thoma
• 3. Biopharmaceutics and Immunogenicity of Biotherapeutics - Balaji Agoram, Kazuko Sagawa, Ravi M Shanker and Satish Singh
• 4. Preformulation Research of Parenteral Medication - Murti Vemuri
• 5. Formulation Development of Small and Large Volume Injections - Madhav Kamat and Patrick P. DeLuca
• 6. Solubility and Solubilization Michael Hageman
• 7. Formulation of Depot Delivery Systems - James J. Cunningham, Marc J. Kirchmeier and Sachin Mittal
• 8. Biophysical and Biochemical Characterization of Peptide and Protein Drug Product - Tapan K. Das and James A. Carroll
• 9. Formulation of Protein- and Peptide-based Parenteral Products - Gaozhong Zhu and Y. John Wang
• 10. Development of Ophthalmic Formulations - Paramita Bandyopadhyay, Martin J. Coffey and Mohannad Shawer
• 11. Glass containers for Parenteral Products - Robert Swift
• 12. Plastic Packaging for Parenteral Drug Delivery - Vinod D. Vilivalam and Fran DeGrazio
• 13. Elastomeric Closures for Parenterals - Renaud Janssen
• 14. Parenteral Product Container-Closure Integrity Testing - Dana Morton Guazzo