Rodak’s Hematology, 7th Edition. Clinical Principles and Applications

Make sure you are thoroughly prepared to work in a clinical laboratory. Rodak’s Hematology: Clinical Principles and Applications, 7^th Edition uses hundreds of full-color photomicrographs to help you understand the essentials of hematology and hemostasis. This new edition details the parts and functions of the cell; shows how to accurately identify cells; covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins; and simplifies hemostasis and thrombosis concepts and disorders. Easy to follow and understand, this book also covers key topics, including working in the hematology and hemostasis laboratory; complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics; and laboratory testing of blood cells and body fluid cells.

• NEW! Chapter on Patient Safety in Hematology and Hemostasis.
• NEW! Section on hematology and hemostasis in transgender populations.
• UPDATED! White blood cell chapters are current with the 2022 World Health Organization (WHO) Classification of Haematolymphoid Tumours.
• NEW! Changes in laboratory results associated with COVID-19 and other viral infections.
• NEW! Content and figures on plasma transport, cell communication, and signal transduction.
• NEW! Coverage of CRISPR technology for treatment of hemoglobinopathies and thalassemia.
• UPDATED! Major revision of the Automated Blood Cell Analysis chapter.

CONTENTS

Part I: Introduction to Hematology

1. An Overview of Clinical Laboratory Hematology

2. Patient Safety in Hematology and Hemostasis

3. Quality Assurance in Hematology and Hemostasis Testing
PART II: Blood Cell Production, Structure, and Function

4. Cell Structure and Function

5. Hematopoiesis

6. Erythrocyte Production and Destruction

7. Erythrocyte Metabolism and Membrane Structure and Function

8. Hemoglobin Metabolism

9. Iron Kinetics and Laboratory Assessment

10. Leukocyte Development, Kinetics, and Functions

11. Platelet Production, Structure, and Function
PART III: Laboratory Evaluation of Blood Cells

12. Manual, Semiautomated, and Point-of-Care Testing in Hematology

13. Automated Blood Cell Analysis

14. Examination of the Peripheral Blood Film and Correlation with the Complete Blood Count

15. Bone Marrow Examination
PART IV: Erythrocyte Disorders

16. Anemias: Red Blood Cell Morphology and Approach to Diagnosis

17. Disorders of Iron Kinetics and Heme Metabolism

18. Anemias Caused by Defects of DNA Metabolism

19. Bone Marrow Failure

20. Introduction to Increased Destruction of Erythrocytes

21. Intrinsic Defects Leading to Increased Erythrocyte Destruction

22. Extrinsic Defects Leading to Increased Erythrocyte Destruction – Nonimmune Causes

23. Extrinsic Defects Leading to Increased Erythrocyte Destruction – Immune Causes

24. Hemoglobinopathies (Structural Defects in Hemoglobin)

25. Thalassemias
PART V: Leukocyte Disorders

26. Nonmalignant Leukocyte Disorders

27. Introduction to Hematologic Neoplasms

28. Flow Cytometric Analysis in Hematologic Disorders

29. Molecular Diagnostics in Hematopathology

30. Cytogenetics

31. Acute Leukemias

32. Myeloproliferative Neoplasms

33. Myelodysplastic Neoplasms

34. Mature Lymphoid Neoplasms
PART VI: Hemostasis and Thrombosis

35. Normal Hemostasis

36. Hemorrhagic Disorders and Laboratory Assessment

37. Qualitative Disorders of Platelets and Vasculature

38. Quantitative Disorders of Platelets: Thrombocytopenia and Thrombocytosis

39. Thrombotic Disorders and Laboratory Assessment

40. Antithrombotic Therapies and Laboratory Assessment

41. Laboratory Evaluation of Hemostasis

42. Hemostasis and Coagulation Instrumentation
PART VII: Hematology and Hemostasis in Selected Populations

43. Hematology and Hemostasis in the Pediatric, Pregnant, Geriatric, and Transgender Populations
E1. Safety in the Hematology Laboratory
E2. Blood Specimen Collection
E3. Care and Use of the Microscope
E4. Body Fluid Analysis in the Hematology Laboratory
Appendix A: Abbreviations
Appendix B: List of Formulas
Appendix C: Answers
Appendix D: Glossary