Female and Male Fertility Preservation

The book offers an essential reference guide for all physicians, specialists or not, seeking to improve their grasp of female and male fertility preservation.

Female Fertility Preservation

1. Front Matter

   Pages 1-1
1. Normal Ovarian Ageing

   Frank J. Broekmans, Annelien C. de Kat

   Pages 3-14
2. The Effect of Chemotherapy on the Ovary Clinical and Pathophysiological Review

   Noam Domniz, Dror Meirow, Hila Raanani, Hadassa Roness

   Pages 15-34
3. Ovarian Function and Fertility Preservation for Young People Treated for Cancer

   S. Caprioli, T. W. Kelsey, W. H. B. Wallace

   Pages 35-45
4. ART in Cancer Survivors

   Elizabeth Ginsburg, Maren Shapiro

   Pages 47-66
5. Fertility-Sparing Strategy in Ovarian Tumors

   Sebastien Gouy, Amandine Maulard, Stéphanie Scherrier, Philippe Morice

   Pages 67-74
6. Ovarian Transposition

   Henri Azaïs, Geoffroy Canlorbe, Jérémie Belghiti, Catherine Uzan

   Pages 75-84
7. Hormonal Suppression for Ovarian Protection

   Eva Blondeaux, Stefano Spinaci, Matteo Lambertini

   Pages 85-95
8. Oocyte and Embryo Cryopreservation: Methodology and Clinical Results

   Ana Cobo, Aila Coello, Megan Hassane, José Remohí

   Pages 97-118
9. Ovarian Stimulation for Fertility Preservation (Different Protocols)

   Lilli Zimmerman, Stephanie Willson, Robert Setton, Glenn Schattman

   Pages 119-129
10. In Vitro Maturation of Oocytes

    Michel De Vos

    Pages 131-142
11. Ovarian Tissue Cryopreservation and Transplantation: Scientific and Clinical Implications

    Sherman Silber, Sierra Goldsmith

    Pages 143-161
12. Techniques for Ovarian Tissue Transplantation

    Jacques Donnez, Luciana Cacciottola, Marie-Madeleine Dolmans

    Pages 163-174
13. Assessing Safety in Ovarian Tissue Transplantation

    Marie-Madeleine Dolmans, Rossella Masciangelo

    Pages 175-183
14. Fertility Preservation in Breast Cancer Patients

    Loris Marin, Volkan Turan, Kutluk Oktay

    Pages 185-198
15. Managing the Infertility Patient with Endometriosis

    Natalia C. Llarena, Swapna Kollikonda, Tommaso Falcone, Rebecca L. Flyckt

    Pages 199-215
16. Severe Autoimmune Diseases

    Melanie Henes, Michael von Wolff, Joerg Henes

    Pages 217-223
17. Fertility Preservation Considerations in Female Patients with Benign and Malignant Hematologic Disease

    Man-wa Lui, W. Hamish B. Wallace, Richard A. Anderson

    Pages 225-237
18. Fertility Preservation in Transgender Males

    Kenny A. Rodriguez-Wallberg

    Pages 239-245

    1. Female Fertility Preservation

       1. Fertility Preservation in Turner Syndrome and Other Gonadal Dysgenesis

          Julie Labrosse, Michael Grynberg

          Pages 247-262
       2. Follicle Activation by Physical Methods and Clinical Applications

          Melody Devos, Isabelle Demeestere, Johanne Grosbois

          Pages 263-278
       3. Fertility Preservation in Children and Adolescents

          Isabelle Demeestere

          Pages 279-292
       4. Elective Egg Freezing

          Marcia C. Inhorn, Daphna Birenbaum-Carmeli, Pasquale Patrizio

          Pages 293-299
       5. Ovarian Tissue Banking to Postpone Menopause

          C. Yding Andersen, S. Jouhari, L. S. Mamsen, S. O. Skouby

          Pages 301-310
       6. Stem Cell Therapy to Approach Refractory Asherman’s Syndrome

          Xavier Santamaria Costa

          Pages 311-319
       7. Uterus Transplantation in the Context of Fertility Preservation

          Mats Brännström

          Pages 321-329
       8. Surrogacy

          Rebecca Miriam Patrizio, Pasquale Patrizio

          Pages 331-339
       9. Medical Treatments for Ovarian Protection

          Charlotte Sonigo, Isabelle Beau, Nadine Binart, Michael Grynberg

          Pages 341-352
       10. Transplantation of Isolated Follicles and the Engineered Ovary

           Christiani A. Amorim, Parinaz Asiabi, Emna Ouni, Janice Vilela, Alessandra Camboni, Maria C. Chiti

           Pages 353-367
       11. In Vitro Perfusion of the Whole Ovary

           M. Milenkovic, Kenny A. Rodriguez-Wallberg, Pasquale Patrizio

           Pages 369-373
       12. Culture of Human Ovarian Follicles from Primordial Stages to Maturity

           Evelyn E. Telfer

           Pages 375-385
       13. Automation in Oocyte and Ovarian Tissue Vitrification

           Amir Arav, Pasquale Patrizio

           Pages 387-394
       14. Gamete Production from Stem Cells

           Krista Maye Symosko, Gerald Schatten, Charles Allen Easley IV

           Pages 395-407
       15. Techniques of Ovarian Transplantation

           Jessica Subirá

           Pages 409-415

    2. Male Fertility Preservation

       1. Front Matter

          Pages 417-417
    3. Impact of Cancer Treatment on Testicular Function

       Rod T. Mitchell, Sheila Lane, Mark Brougham

       Pages 419-439
    4. ART in Male Cancer Patients Including Sperm Donation

       Luciano Negri, Pasquale Patrizio, Paolo Emanuele Levi-Setti

       Pages 441-452
    5. Sperm Cryopreservation

       Biljana Popovic Todorovic, Greta Verheyen, Veerle Vloeberghs, Herman Tournaye

       Pages 453-470
    6. Indications and Methods of Epididymal or Testicular Sperm Retrieval for Cryopreservation

       Caroline Kang, Nahid Punjani, James A. Kashanian

       Pages 471-486

       1. Male Fertility Preservation

          1. Testis-Sparing Surgery

             Eric Huyghe

             Pages 487-496
          2. Fertility Preservation in Hypogonadal Men

             Jordan Cohen, Andrew Rezk, Ranjith Ramasamy

             Pages 497-515
          3. Genital Affirmation Surgery for Patients Assigned Male at Birth

             Cecile A. Ferrando

             Pages 517-528
          4. Testicular Tissue Transplantation

             Dorien Van Saen, Ellen Goossens

             Pages 529-554
          5. Removal of Malignant Cells Before Autotransplantation of Spermatogonial Stem Cells

             Omar Abdelaal, Hooman Sadri-Ardekani

             Pages 555-569
          6. Transplant Therapies for Male Infertility

             Kien Tran, Sarah K. Munyoki, Amanda C. Zielen, Richard N. Yu, Kyle E. Orwig

             Pages 571-585
          7. In Vitro Spermatogenesis

             Christine Wyns, Marc Kanbar

             Pages 587-607

       2. Fertility Preservation Considerations

          1. Front Matter

             Pages 609-609
       3. Psychological Aspects of Fertility Preservation

          Verena Ehrbar, Sibil Tschudin

          Pages 611-626
       4. Ethical Considerations of Fertility Preservation

          Heidi Mertes, Guido Pennings

          Pages 627-640
       5. Legal Aspects of Fertility Preservation

          Clio Sophia Koller, Katherine L. Kraschel

          Pages 641-658

          
          

          About the editors

          ​Prof. Michaël Grynberg is an obstetrician gynecologist specialized in reproductive medicine. He completed his PhD on the regulation of follicular growth and AMH production. In 2014, he became a Professor of Reproductive Medicine and head of the Department of Reproductive Medicine & Fertility Preservation at the University Hôpital Jean Verdier, Bondy, France. Since mid-2017, he has been head of the Department of Reproductive Medicine & Fertility Preservation at the University Hôpital Antoine Béclère, Clamart, France.  In addition, he is an active member of the basic research unit INSERM U 1133, Université Paris Diderot-CNRS UMR 8251. His research interests initially included the assessment of ovarian follicular status and the regulation of anti-Müllerian hormone, a key peptide in ovarian function. Over the past 5 years, he has expanded his field of research to include onco-fertility. Indeed, female fertility preservation has recently emerged in the field of reproductive medicine. Michaël Grynberg is a pioneer on female fertility preservation in France and has recently become the President of the French Society of Onco-Fertililty. He is also deputy of the fertility preservation special interest group of the ESHRE and Head of the Fertility Department at the French College of Obstetrician Gynecologists. Prof. Grynberg has authored or co-authored over 150 peer-reviewed articles in international journals and books.

          Dr Pasquale Patrizio is an internationally recognized, board-certified specialist in Obstetrics & Gynecology, Reproductive Endocrinology and Infertility, and Andrology, and holds a Master in Bioethics.  He is a Professor and Director of the Yale University Fertility Center and Fertility Preservation Program.  He is an associate editor for the Journal of Assisted Reproduction and Genetics, and a section editor for both the American Journal of Obstetrics and Gynecology, and Reproductive BioMedicine Online. He was a founding member of the International Society for Fertility Preservation (ISFP) and served as President from 2015 to 2016. He has authored 6 books, nearly 500 articles and book chapters, and holds 2 US patents (in diagnostics and therapeutics).  Among his many contributions to the field, he co-pioneered the Microsurgical Epididymal Sperm Aspiration (MESA) technique; discovered that congenital absence of the vas deferens is a mild, genital form of cystic fibrosis; reported on microdeletions on the Yq chromosome responsible for severe oligospermia; introduced methods for assessing oocyte quality using genetic analysis of cumulus cells; and identified causes of oocyte aging as secondary to follicular and cumulus cell hypoxia.  His main research interests include:  Improving the efficiency of ART, ovarian aging, fertility preservation strategies for cancer and non-medical conditions, ovarian and testicular tissue vitrification, and methods for freeze-drying gametes and stem cells.