The Hippocampus Book Second Edition

Long known to be important for memory, the hippocampus has been a prime focus for neuroscience research for years. This second edition of The Hippocampus Book highlights advances in our understanding of this group of brain structures and includes a new set of translational chapters concerning associated brain disorders. This edition brings together contributions by leading international experts on hippocampal anatomy, physiology, molecular biology and function with other chapters summarizing how disorders of hippocampal function contribute to several neurologic and psychiatric conditions.

Concurrently, this text illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, neural and synaptic plasticity, cognition and behaviour, and computational algorithms. Covering theory, experimental data and translational relevance, this uniquely authoritative work vividly illustrates the progress that continues to be made in unravelling the workings of the brain. The Hippocampus Book will be of interest to those working in a range of neuroscientific disciplines, ranging from the molecular biology of neural function and dysfunction, through network physiology to behavior and neuropathology and take pride of place on the bookshelves of all with an interest in the brain and its functions.

• Written by world experts on the hippocampus, including two Nobel Laureates, and four winners of The Brain Prize
• Comprehensive update on the astonishing developments in our understanding of hippocampal formation and serves as an essential text in the neuroscience field
• Offers a unique link between neurobiological studies of normal hippocampal function and relevant brain disorders

CONTENTS

Chapter 1: Introduction: The Hippocampal Formation – the Editors
Chapter 2: Historical Perspective – the Editors
Chapter 3: Neuroanatomy – David Amaral, Pierre Lavenex, and Ricardo Insausti
Chapter 4: Development of the Hippocampus – Pierre Lavenex, David Amaral, Pamela Banta Lavenex, Francois Guillemot, Ricardo Insausti, and Noelia Urban
Chapter 5: Cell Properties – Nelsonn Spruston Rebecca Piskorowski, Viven Chevaleyre, Mark D. Eyre, Chris McBain, and Marlene Bartos
Chapter 6: Synaptic Function – Dimitri Kullman and Kirill Volynski
Chapter 7: Local Circuits – Andres D. Grosmark, Aaron D. Milstein, Attila Losonczy, and Ivan Soltesz
Chapter 8: Molecular Mechanisms of Synaptic Function in the Hippocampus – Paul G Donlin-Asp, Anne-Sophie Hafner, and Erin M Schuman
Chapter 9: Structural Plasticity – Rusty Gage, Matthew Shtrahman, Sarah Parylak, and Tomohisa Toda
Chapter 10: Synaptic Plasticity in the Hippocampus – Tim Bliss, Graham Collingridge, Sam Cooke, John Georgiou, and Richard Morris
Chapter 11: Hippocampal Physiology – Julia Krupic and John O’Keefe
Chapter 12: The Entorhinal Cortex – Benjamin R. Kanter, Edvard I. Moser, and Menno P. Witter
Chapter 13: Functions of the Human Hippocampus – Daniel N. Barry and Eleanor A. Maguire
Chapter 14: Theories of Hippocampal Function – Sam Mackenzie, Francesco Gobbo, and Richard Morris
Chapter 15: Aging and the Hippocampus – Sara N. Burke and Carol Barnes
Chapter 16: Computational Models of Hippocampal Cognitive Function – Daniel Bush and Neil Burgess
Chapter 17: Stress and the Hippocampus – Bruce McEwen with Sumantra Chatterji
Chapter 18: Mesial Temporal Lobe Epilepsy – Matthew C. Walker, Maria Thom, and Umesh Vivekananda
Chapter 19: Psychosis and the Hippocampus: Fundamental Alterations in Hippocampal Function – Carol Tamminga, Daniel Scott, and Elena I. Ivleva
Chapter 20: Alzheimer Disease – Dennis Chan, Tara Spires-Jones, Frank Provenzano, Lizzie Glennon, and Karen Duff