Thermodynamics and Biophysics of Biomedical Nanosystems Applications and Practical Considerations

• Highlights the recent advances of thermodynamics and biophysics in drug delivery nanosystems and in biomedical nanodevices
• 
  
• Provides an in depth knowledge of bio-inspired nanotechnological systems for pharmaceutical applications
• 
  
• Features on new aspects of biophysics and thermodynamics as important elements for evaluating biomedical nanosystems

This book highlights the recent advances of thermodynamics and biophysics in drug delivery nanosystems and in biomedical nanodevices. The up-to-date book provides an in-depth knowledge of bio-inspired nanotechnological systems for pharmaceutical applications.

Biophysics and thermodynamics, supported by mathematics, are the locomotive by which the drug transportation and the targeting processes will be achieved under the light of the modern pharmacotherapy. They are considered as scientific tools that promote the understanding of physicochemical and thermotropic functionality and behavior of artificial cell membranes and structures like nanoparticulate systems. Therefore, this book focusses on new aspects of biophysics and thermodynamics as important elements for evaluating biomedical nanosystems, and it correlates their physicochemical, biophysical and thermodynamical behaviour with those of a living organism.

Table of contents (13 chapters)

• Introducing Thermodynamics and Biophysics in Health Sciences

  Demetzos, Costas (et al.)

  Pages 1-11

• Methodological Approaches for the Characterization of the Self-assembling Behaviour in the Pharmaceutical Field

  Perinelli, Diego Romano (et al.)

  Pages 13-37

• Phase Transitions in Biological Membranes

  Heimburg, Thomas

  Pages 39-61

• Isothermal Titration Calorimetry: A Powerful Tool for the Characterization of Molecular Interactions

  Thanassoulas, Angelos (et al.)

  Pages 63-103

• Dynamics of Iron Homeostasis in Health and Disease: Molecular Mechanisms and Methods for Iron Determination

  Ploumi, Christina (et al.)

  Pages 105-145

• Achieving Selective Targeting Using Engineered Nanomaterials

  Lanfranco, Roberta (et al.)

  Pages 147-182

• PAMAM and PPI Dendrimers in Biophysical and Thermodynamic Studies on the Delivery of Therapeutic Nucleotides, Nucleosides and Nucleobase Derivatives for Anticancer Applications

  Gorzkiewicz, Michał (et al.)

  Pages 183-243

• Thermal Analysis of Glass-Ceramics and Composites in Biomedical and Dental Sciences

  Theodorou, George S. (et al.)

  Pages 245-295

• Differential Scanning Calorimetry (DSC): An Invaluable Tool for the Thermal Evaluation of Advanced Chimeric Liposomal Drug Delivery Nanosystems

  Chountoulesi, Maria (et al.)

  Pages 297-337

• Drug-Membrane Interactions in the Renin Angiotensin System

  Ntountaniotis, Dimitrios (et al.)

  Pages 339-364

• Biophysical Characterization of Polysialic Acid—Membrane Nanosystems

  Sapoń, Karolina (et al.)

  Pages 365-396

• Self-assembling of Thermo-Responsive Block Copolymers: Structural, Thermal and Dielectric Investigations

  Kyritsis, A. (et al.)

  Pages 397-444

• Sol-Gel Synthesis and Characterization of Hybrid Materials for Biomedical Applications

  Catauro, Michelina (et al.)

  Pages 445-475