Vitamin C. New Biochemical and Functional Insights

Vitamin C holds a unique place in scientific and cultural history. In this book, a group of leading scientific researchers describe new insights into the myriad ways vitamin C is employed during normal physiological functioning. In addition, the text provides an extensive overview of the following: the rationale for utilizing vitamin C in the clinic, updates on recent uses of vitamin C in cancer treatment through high-dose intravenous therapies, the role vitamin C plays in the treatment of sepsis and infectious disease, management of the ways vitamin C can improve stem cell differentiation, as well as vitamin C use in other important health situations.

• Includes chapters from a team of leading international scholars
• Reviews the history and recent research on the functions, benefits, and uses of vitamin C
• Focuses special attention on the way vitamin C can be used in the treatment of cancers
• Discusses how vitamin C can be employed against infectious disease

Table of Contents

Part I Overview of Vitamin C. 1. A "C Odyssey": Recommended Dietary Allowances and Optimal Health: Paradigm and Promise of Vitamin C. Part II Chemistry and Biology of Vitamin C. 2. Chemistry and Biochemistry of Vitamin C in Mammalian Systems. 3. Vitamin C Alimentation via SLC Solute Carriers. 4. Vitamin C Pharmacokinetics. 5. Ascorbate as an Enzyme Cofactor. 6. Role of Ascorbate and Dehydroascorbic Acid in Metabolism of the Cell. Part III Vitamin C and Immune Function. 7. Vitamin C in Pneumonia and Sepsis. 8. Vitamin C in Immune Cell Function. 9. Role of Vitamin C in Chronic Wound Healing. Part IV Vitamin C and Neurological Function. 10. Vitamin C in Neurological Function and Neurodegenerative Disease. 11. Vitamin C and the Brain. 12. Epigenetic Role of Vitamin C in Neurological Development and Disease.