Myelodysplastic Syndromes: Pathobiology and Clinical Management, Second Edition Series: Basic and Clinical Oncology

• del(5q) and 5q-syndrome, CMML, and MDS-MPD overlap syndrome
• reborn DNA methyltransferase inhibiting nucleoside analogs; chronic myelomonocytic leukemia and other cases with myeloproliferative features
• mitochondria and iron overload in MDS
• global genomics approaches (cDNA expression arrays, array-based comparative genomic hybridization, and single nucleotide polymorphism arrays)
• the role of abnormal mitochondrial ferritin accumulation and other mitochondrial metabolic anomalies in MDS
• other disease-associated alterations (abnormalities of B lymphocyte populations in MDS)
• recently approved drugs: azacitidine, lenalidomide, and decitabine