Gene Therapy for Neurological Disorders. Molecular Approaches for Targeted Treatment

Neurological illnesses pose one of the biggest hazards to the healthcare system today. This new book brings together the latest methods of gene therapy that can be used to treat both inherited and sporadic neurodegenerative diseases. It presents the most significant advances in gene transfer methods as well as the most recent understandings of the mechanisms behind specific neurodegenerative illnesses, placing these into the context of gene therapy approaches for the central nervous system. The book introduces the basics of neurodegenerative conditions and the physiological basis for their occurrence in humans. It also discusses the various proteins useful in neuro diseases and their viral applications. The book explores how stem cells can be used to learn about the future of gene therapy along with the significance of the sequences that silence genes. It discusses the functions of astrocytes in different brain regions, as well as in-vivo research in gene therapy for neurodegenerative disorders.

CONTENTS

1. Neurodegenerative Disorders and Their Treatment

2. Neurodegenerative Disorder: A Mysterious Group of Diseases

3. Neurodegenerative Diseases Spread Like Prion Viruses

4. Gene Therapy: A Promising Strategy for the Treatment of Brain Disease

5. Stem-Cell-Employed Gene Therapy for Neurodegenerative Disorders

6. Current Practice and Prospects in Gene Therapy Based on Genomic DNA

7. Targeting Oligodendrocytes with Gene-Silencing Sequences through Vector-Mediated Transgene Delivery

8. Astrocytes: Genetic Treatment Targets for Alzheimer‘s Disease

9. Clinical Studies of Gene Therapy for the Treatment of Neurodegenerative Disorders