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Muscle Biopsy: A Practical Approach, 4th Edition

Muscle Biopsy: A Practical Approach, 4th Edition
Muscle Biopsy: A Practical Approach, 4th Edition
  • Συγγραφείς: DubowitzSewry & Oldfors
  • ISBN: 9780702043406
  • Εκδότης: ELSEVIER
  • Σελίδες: 592
  • Διαστάσεις: 184 X 260 mm
  • Έτος Έκδοσης: 2013
232,90€
Χωρίς ΦΠΑ: 219,72€

By Victor Dubowitz, MD, PhD, FRCP, FRCPCH, Emeritus Professor of Paediatrics Dubowitz Neuromuscular Centre Faculty of Medicine Imperial College London Hammersmith Campus London; Caroline A. Sewry, BSc, PhD, FRCPath, Professor of Muscle Pathology, Dubowitz Neuromuscular Centre, Imperial College Faculty of Medicine, Hammersmith Hospital, London, UK; Centre for Inherited Neuromuscular Disorders, Department of Histopathology, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, UK and Anders Oldfors, MD PhD, Professor and Director Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden
 
Description:

Muscle Biopsy: A Practical Approach gives you all of the unparalleled guidance necessary to effectively interpret and diagnose muscle biopsy specimens for the full range of diseases in both adults and children. Authored by Dr. Victor Dubowitz, an internationally renowned figure in the field of muscle disease, this medical reference book takes an integrated approach to diagnosis and assessment of muscle biopsies that includes clinical, genetic, biochemical, and pathological features. It's the comprehensive, up-to-date coverage you need to evaluate muscle disorders with confidence.


 
Features:
    • Bridge the gap between clinical syndromes/disorders and their underlying
    • Understand and apply expert techniques for obtaining a muscle biopsy, and familiarize yourself with the histochemical, histological, electron microscopical, and molecular appearance of normal muscle and the pathology of individual muscle disease.
    • Read the entire contents and download all of the images online at Expert Consult.
    pathologies with the guidance of muscle disease expert, Dr. Victor Dubowitz, who skillfully guides you through the complexities of pathologic diagnoses and their implications for clinical treatment.
New To This Edition:
    • Apply all of the latest diagnostic techniques for neurodegenerative and genetic diseases
    • Stay current in practice with state-of-the-art coverage of genetic markers for individual conditions and antibodies used in immunocytochemical diagnosis.
    • Understand the genetics of muscular dystrophies with absolute clarity through the use of brilliantly simple diagrams and tables, and compare your specimens to a wealth of superb color images capturing the full spectrum of muscle biopsy findings.
    • Take advantage of international insights and fresh perspectives in muscle diseases and disorders from new author Dr. Anders Oldfors, from the Department of Pathology, University of Goteborg, Sweden.
    with a brand-new chapter on myopathies associated with systemic disorders and aging, and use advanced techniques such as immunohistochemistry and immunoblotting to produce the most accurate diagnoses possible for a full range of muscle disorders.
Table Of Contents:
Section 1 The Biopsy: Normal and Diseased Muscle

1. The procedure of muscle biopsy

2. Histological and histochemical stains and reactions

3. Normal muscle

4. Definition of pathological changes seen in muscle biopsies

5. Ultrastructural changes in diseased muscle

6. Immunohistochemistry

7. How to read a biopsy


Section 2 Pathological Muscle: Individual Diseases

8. Classification of neuromuscular disorders

9. Neurogenic disorders

10. Muscular dystrophies and allied disorders I: Duchenne and Becker muscular dystrophy

11. Muscular dystrophies and allied disorders II: limb-girdle muscular dystrophies

12. Muscular dystrophies and allied disorders III: congenital muscular dystrophies

13. Muscular dystrophies and allied disorders IV: Emeryƒ{Driefuss muscular dystrophies and Bethlem myopathy

14. Muscular dystrophies and allied disorders V: facioscapulohumeral dystrophy, myotonic dystrophy, oculopharyngeal muscular dystrophy

15. Congenital myopathies

16. Myofibrillar myopathies

17. Metabolic myopathies I: glycogenoses

18. Metabolic myopathies II: lipid related disorders and mitochondrial myopathies

19. Endocrine disorders

20. Ion channel disorders

21. Myasthenic syndromes

22. Inflammatory myopathies

23. Toxic and drug-induced myopathies
Russell Lane, Charing Cross Hospital


Appendix 1. Glossary of commonly used terms


References


Index
 

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