Synbiotics in Metabolic Disorders. Mechanisms, Therapeutic Potential, and Future Perspectives

This book explores the potential role of prebiotics, probiotics, and synbiotics in managing various metabolic disorders, chronic diseases, and metabolic syndromes. The initial chapter provides an overview of metabolic disorders, including their classification, symptoms, and underlying causes. Additionally, the chapter discusses the intricate signaling pathways and mechanisms through which prebiotics, probiotics, and synbiotics interact with the human body in relation to type-2 diabetes, obesity, Phenylketonuria, and Hemochromatosis. Additionally, the book highlights the potential impact of probiotics and synbiotics on oxidative stress, inflammation, lipid metabolism, and blood pressure. Furthermore, this book focuses on the gut-brain axis and how synbiotics may influence neurotransmitter metabolism. With an emphasis on the gut-microbiota axis, this book presents a compelling narrative that explores the rationality behind synbiotic use and offers a glimpse into future perspectives for managing metabolic disorders effectively. This book is intended for researchers in the fields of nutraceuticals, nanomedicine, endocrinology, nutrition, gastroenterology, and metabolic medicine who are working in the field of probiotics, prebiotics, and symbiotics for the treatment of metabolic disorders

CHAPTER 4: SYNBIOTICS AND GUT MICRO FLORA: MECHANISMS AND THERAPEUTIC RATIONALITY AND CLINICAL APPLICATIONS FOR MANAGEMENT OF TYPE-2 DIABETES

Nisha Sharma¹, Prakash Chandra Gupta¹, Swarnakshi Upadhyay¹, Kamla Pathak^2*

Chapter 5: Therapeutic Potential of Gut Microbiota in Metabolic Disorders

Akash Kumar¹, Jhilam Pramanik ², Nandani Goyal3, Mukesh Kumar⁴, Aarzoo Jangra¹, Bhagavathi Sundaram Sivamaruthi ^{5, 6,} Bhupender Prajapati ⁷, Sudarshan Singh ^5,8*, Popat Mohite ⁹, Abhijeet Puri⁹

Chapter 6: Therapeutic Potential of Gut Microbiota in Metabolic Disorders

Anas Islam, Aditya Singh, Asad Ahmad, Badruddeen¹, Juber Akhtar¹, Usama Ahmad¹, Mohammad Irfan Khan¹, Mohammad Ahmad, Yusuf Asad^2*

Chapter 7: The Impact of probiotic and synbiotic supplementation on oxidative stress and inflammation

Himanshu Sharma¹, Sanjesh Kumar², Sumel Ashique^3*, Pratibha Bhowmick³, Radheshyam Pal⁴, Arshad Farid⁵, Roomah Javed⁵, Farzad Taghizadeh-Hesary ^6,7 , Subhajit Mandal⁸

Chapter 8: Correlation and Successive Role of Synbiotics to Manage Blood Pressure

Himanshu Sharma^1*, Monika Kaushik², Venishaa S³, Rashmi Pathak⁴, Arshad Farid⁵, Mithun Bhowmick⁶

Chapter 9: Synbiotics: A novel paradigm for Phenylketonuria management by targeting gut-microbiota and get-brain axis

Sana Fatima¹, Muhammad Muzammal¹, Shaista Naz¹, Muzammil Ahmad Khan¹, Alamgir Khan¹, Arshad Farid¹, Wasim shah^2*

Chapter 10: Synbiotic: Potential Role in Hemochromoatosis Management

Monika Kaushik^1*, Himanshu Sharma², Prathap Madeswaraguptha¹, Venishaa S³, Murugesan Vanangamudi¹

Chapter 11: Correlation between synbiotic supplements and lipid metabolism: a novel strategy to counter attack metabolic disorders

Alamgir Khan¹, Arshad Farid¹, Fazal Haq², Sohail Ahmad¹, Amin Ullah³, Muhammad Muzammal¹, Muhammad Ajmal Khan^4*

Chapter 12: PROBIOTICS, PREBIOTICS, AND POSTBIOTICS ON METABOLIC DISEASES TARGETING GUT MICROBIOTA

Priyanka Ray¹, Mohammad Abdul Faseeh², Debojyoti Adak^2*, Himanshu Sharma³

Chapter 13: Impact of Bacterial metabolites on the gut environment to manage metabolic disorders

Sohail Ahmad¹, Maria Faraz¹, Muhammad Badar¹, Alamgir Khan¹, Roomah Javed¹, Arshad Farid ^1*

Chapter 14: The Potential Role of Prebiotics, Probiotics, and Synbiotics in Cancer Prevention and Therapy

Phool Chandra^1*, Himanshu Sharma¹, Neetu Sachan²

Chapter 15: Key regulatory aspects of prebiotics, probiotics, and synbiotics in the management of metabolic disorders

Innocent Ayesiga¹, Shabnoor Iqbal², Yusuf Kyejjusa^3,4, Joash Okoboi⁵, Timothy Omara⁶, Thomas Adelina⁷, Delafrique Deogratias⁸, Arthur Amule Anyole⁸, Braize Ben Kagimu⁸, Denis Odongo⁸, Ivan Kahwa

Chapter 16: Synbiotics: Present Status and Future Prospectives to Control Metabolic Disorders

Sanzia Mehjabin¹, Md. Khokon Miah Akanda^2*, A. H. M. Nazmul Hasan², G. M. Masud Parvez